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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Salvi, Amrita; Young, Alexandria N; Huntsman, Andrew C; Pergande, Melissa R; Korkmaz, Melissa A; Rathnayake, Rathnayake A; Mize, Brittney K; Kinghorn, A Douglas; Zhang, Xiaoli; Ratia, Kiira; Schirle, Markus; Thomas, Jason R; Brittain, Scott M; Shelton, Claude; Aldrich, Leslie N; Cologna, Stephanie M; Fuchs, James R; Burdette, Joanna E.
Afiliación
  • Salvi A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Young AN; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Huntsman AC; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
  • Pergande MR; Department of Chemistry, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Korkmaz MA; Department of Chemistry, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Rathnayake RA; Department of Chemistry, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Mize BK; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
  • Kinghorn AD; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
  • Zhang X; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, 43210, USA.
  • Ratia K; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Schirle M; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Thomas JR; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Brittain SM; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Shelton C; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Aldrich LN; Department of Chemistry, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Cologna SM; Department of Chemistry, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Fuchs JR; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
  • Burdette JE; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60607, USA. joannab@uic.edu.
Cell Death Dis ; 13(1): 45, 2022 01 10.
Article en En | MEDLINE | ID: mdl-35013112
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Autofagia / Núcleo Celular / ATPasas de Translocación de Protón / Cistadenocarcinoma Seroso / Proteína de Susceptibilidad a Apoptosis Celular / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Death Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Autofagia / Núcleo Celular / ATPasas de Translocación de Protón / Cistadenocarcinoma Seroso / Proteína de Susceptibilidad a Apoptosis Celular / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Death Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido