Reduced Levels of ABCA1 Transporter Are Responsible for the Cholesterol Efflux Impairment in ß-Amyloid-Induced Reactive Astrocytes: Potential Rescue from Biomimetic HDLs.

Sierri, Giulia; Dal Magro, Roberta; Vergani, Barbara; Leone, Biagio Eugenio; Formicola, Beatrice; Taiarol, Lorenzo; Fagioli, Stefano; Kravicz, Marcelo; Tremolizzo, Lucio; Calabresi, Laura; Re, Francesca

Sierri, Giulia; Dal Magro, Roberta; Vergani, Barbara; Leone, Biagio Eugenio; Formicola, Beatrice; Taiarol, Lorenzo; Fagioli, Stefano; Kravicz, Marcelo; Tremolizzo, Lucio; Calabresi, Laura; Re, Francesca.

Afiliación

Sierri G; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Dal Magro R; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Vergani B; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Leone BE; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Formicola B; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Taiarol L; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Fagioli S; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Kravicz M; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Tremolizzo L; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Calabresi L; Department of Pharmacological and Biomolecular Science, Centro Grossi Paoletti, University of Milan, 20133 Milan, Italy.
Re F; BioNanoMedicine Center NANOMIB, School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.

Int J Mol Sci ; 23(1)2021 Dec 22.

Article en En | MEDLINE | ID: mdl-35008528

Asunto(s)

Transportador 1 de Casete de Unión a ATP/metabolismo; Péptidos beta-Amiloides/metabolismo; Astrocitos/metabolismo; Colesterol/metabolismo; Lipoproteínas HDL/metabolismo; Enfermedad de Alzheimer/metabolismo; Apolipoproteína A-I/metabolismo; Transporte Biológico/fisiología; Biomimética/métodos; Barrera Hematoencefálica/metabolismo; Encéfalo/metabolismo; Línea Celular; Humanos

Palabras clave

ABCA1; Alzheimer disease; HDL; apoA-I nanodiscs; astrocytes; brain cholesterol; nanoparticles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Astrocitos / Colesterol / Péptidos beta-Amiloides / Transportador 1 de Casete de Unión a ATP / Lipoproteínas HDL Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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