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Design, Spectral Characteristics, and Possibilities for Practical Application of BODIPY FL-Labeled Monoterpenoid.
Guseva, Galina B; Antina, Elena V; Berezin, Mikhail B; Pavelyev, Roman S; Kayumov, Airat R; Ostolopovskaya, Olga V; Gilfanov, Ilmir R; Frolova, Larisa L; Kutchin, Alexander V; Akhverdiev, Rustem F; Lisovskaya, Svetlana A; Trizna, Elena Y; Lodochnikova, Olga A; Islamov, Daut R; Efimov, Sergey V; Klochkov, Vladimir V; Khodov, Ilya A; Boichuk, Sergei V; Nikitina, Liliya E.
Afiliación
  • Guseva GB; G.A. Krestov Institute of Solution Chemistry of Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russian Federation.
  • Antina EV; G.A. Krestov Institute of Solution Chemistry of Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russian Federation.
  • Berezin MB; G.A. Krestov Institute of Solution Chemistry of Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russian Federation.
  • Pavelyev RS; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Kayumov AR; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Ostolopovskaya OV; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Gilfanov IR; Kazan State Medical University, 420012 Kazan, Russian Federation.
  • Frolova LL; Institute of Chemistry, Federal Research Center "Komi Scientific Centre", 167000 Syktyvkar, Russian Federation.
  • Kutchin AV; Institute of Chemistry, Federal Research Center "Komi Scientific Centre", 167000 Syktyvkar, Russian Federation.
  • Akhverdiev RF; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Lisovskaya SA; Kazan State Medical University, Scientific Research Institute of Epidemiology and Microbiology, 420012 Kazan, Russian Federation.
  • Trizna EY; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Lodochnikova OA; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Islamov DR; Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of Russian Academy of Sciences, 420008 Kazan, Russian Federation.
  • Efimov SV; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Klochkov VV; Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of Russian Academy of Sciences, 420008 Kazan, Russian Federation.
  • Khodov IA; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Boichuk SV; Kazan Federal University, 420008 Kazan, Russian Federation.
  • Nikitina LE; G.A. Krestov Institute of Solution Chemistry of Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russian Federation.
ACS Appl Bio Mater ; 4(8): 6227-6235, 2021 08 16.
Article en En | MEDLINE | ID: mdl-35006906
This article describes the design and biological properties of a BODIPY FL-labeled monoterpenoid BF2-meso-(4-((1″R)-6″,6″-dimethylbicyclo[3.1.1]hept-2″-ene-2″)yl-methoxycarbonylpropyl)-3,3',5,5'-tetramethyl-2,2'-dipyrromethene conjugate (BODIPYmyrt). The fluorophore was characterized using X-ray, NMR, MS, and UV/vis spectroscopy. The conjugate exhibits a high quantum yield (to ∼100%) in the region 515-518 nm. BODIPYmyrt effectively penetrates the membranes of the bacterial and fungal cells and therefore can be used to examine the features of a broad spectrum of Gram-positive and Gram-negative bacteria and pathogenic fungi as well. Moreover, BODIPYmyrt exhibits a moderate tropism to the subcellular structures in mammalian cells (e.g., mitochondria), thereby providing an attractive scaffold for fluorophores to examine these particular organelles.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monoterpenos / Antibacterianos Límite: Animals Idioma: En Revista: ACS Appl Bio Mater Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monoterpenos / Antibacterianos Límite: Animals Idioma: En Revista: ACS Appl Bio Mater Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos