Your browser doesn't support javascript.
loading
Simultaneous adaption of the gain and phase of a generalized transfer function for aortic pressure waveform estimation.
Du, Shuo; Yao, Yang; Sun, Guozhe; Mukkamala, Ramakrishna; Xu, Lisheng.
Afiliación
  • Du S; College of Medicine and Biological and Information Engineering, Northeastern University, Shenyang, 110169, China.
  • Yao Y; School of Information Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Sun G; Department of Cardiology, The First Hospital of China Medical University, Shenyang, 110122, Liaoning, China.
  • Mukkamala R; Department of Bioengineering and Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
  • Xu L; College of Medicine and Biological and Information Engineering, Northeastern University, Shenyang, 110169, China. Electronic address: xuls@bmie.neu.edu.cn.
Comput Biol Med ; 141: 105187, 2022 02.
Article en En | MEDLINE | ID: mdl-34995874
GOAL: This paper proposes and validates a completely adaptive transfer function (CATF) based on an autoregressive exogenous (ARX) model which adjusts the gain and phase of a generalized transfer function (GTF) simultaneously to estimate the aortic pressure waveform from a brachial pressure waveform. METHODS: Invasive aortic and brachial pressure waveforms were recorded from 34 subjects for the validation of the proposed method. Individual transfer functions (ITFs) were trained based on the pressure waveforms using an ARX model. The GTF was derived by averaging the ITFs. CATF was then obtained by adjusting both the gain and phase of the GTF using regression formulas calculated from the ITFs and brachial hemodynamic parameters. Meanwhile the quantitative contributions of the adaption of gain and phase of the GTF were investigated respectively. The root-mean-square-error of the total waveform and absolute errors of common hemodynamic indices including systolic and diastolic blood pressures (SBP and DBP, respectively), pulse pressure (PP) and augmentation index were used to evaluate the performance of the proposed method in the data divided into low, middle and high PP amplification groups. RESULTS: The CATF achieved lower errors for DBP and PP in the low PP amplification group (1.79 versus 2.10 mmHg and 5.08 versus 6.23 mmHg, respectively, both P < 0.05) and PP in the middle amplification group (1.43 versus 1.92 mmHg, P < 0.05) compared with the GTF. SIGNIFICANCE: The proposed method provides a step towards the development of an improved and clinically useful non-invasive approach for estimating the aortic pressure waveform from a peripheral pressure waveform.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Determinación de la Presión Sanguínea / Presión Arterial Límite: Humans Idioma: En Revista: Comput Biol Med Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Determinación de la Presión Sanguínea / Presión Arterial Límite: Humans Idioma: En Revista: Comput Biol Med Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos