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Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein.
Zhong, Jiahong; Li, Mengfan; Xu, Jiangping; Dong, Wenli; Qin, Yunyun; Qiu, Shuqing; Li, Xing; Wang, Haitao.
Afiliación
  • Zhong J; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Li M; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Xu J; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Center for Brain Science and Brain-Inspired Intelligence, Guang
  • Dong W; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Qin Y; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Qiu S; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Li X; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Wang H; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Center for Brain Science and Brain-Inspired Intelligence, Guang
Toxicol Appl Pharmacol ; 436: 115859, 2022 02 01.
Article en En | MEDLINE | ID: mdl-34990728
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivados del Benceno / Ubiquitina-Proteína Ligasas / Alfa-Sinucleína / Furanos / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivados del Benceno / Ubiquitina-Proteína Ligasas / Alfa-Sinucleína / Furanos / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos