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[A cohort study on the incidence of HIV infection in drug abusers among men who have sex with men in Shanghai and Tianjin].
Shan, D; Ning, Z; Zheng, H; Huang, D Y; Yu, M H; Yang, J; Liu, H; Zhang, D P.
Afiliación
  • Shan D; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
  • Ning Z; Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China.
  • Zheng H; Shanghai Xinsheng, Shanghai 200023, China.
  • Huang DY; Shanghai Xinsheng, Shanghai 200023, China.
  • Yu MH; Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.
  • Yang J; Shenlan Public Health Consulting Service Center, Tianjin 300121, China.
  • Liu H; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
  • Zhang DP; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhonghua Liu Xing Bing Xue Za Zhi ; 42(12): 2149-2155, 2021 Dec 10.
Article en Zh | MEDLINE | ID: mdl-34954979
Objective: To analyze the incidence of HIV infection and identify associated risk factors in drug abusers among men who have sex with men (MSM) in Tianjin and Shanghai through a cohort study and provide a basis for HIV prevention in this population. Methods: A prospective cohort study was conducted among MSM who had a history of drug abuse in the past six months from June 2016 to June 2018 in the two cities. MSM were investigated to obtain information on sociodemographic characteristics, HIV-related sexual behaviors, and drug abuse. Follow-up investigation and HIV testing were carried out based on the baseline survey and testing. Cox regression analysis was conducted to identify the risk factors for HIV infection. Results: There were 455 eligible subjects, and 16 new HIV infection cases were identified in the 2-year follow-up survey. The cumulative follow-up time was 586.08 person-years, and the incidence of HIV infection was 2.73/100 person-years. The multivariate Cox regression analysis results showed that compared with those aged ≥25 years, consistent condom use during anal sex with men in the past six months, without mixed-use of drugs, these aged <25 years (HR=5.01, 95%CI: 1.09-23.11), inconsistent condom use during anal sex with men in the past six months (HR=1.58, 95%CI: 1.04-2.41) and mixed-use of drugs (HR=1.92, 95%CI: 1.08-3.40) were significantly associated with HIV infection in this cohort. Conclusions: The younger age, inconsistent condom use during anal sex with men, and mixed drug use appeared as risk factors of new HIV infection in drug abusers among MSM. HIV prevention and intervention in this population should be further strengthened.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Consumidores de Drogas / Minorías Sexuales y de Género Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male País/Región como asunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Consumidores de Drogas / Minorías Sexuales y de Género Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male País/Región como asunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: China