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[Analysis of future liver remnant parameters in children after extended liver resection]. / Analiz parametrov budushchego ostatka pecheni u detei, perenesshikh ee obshirnye rezektsii.
Akhaladze, D G; Rabaev, G S; Likar, Yu N; Kireeva, E D; Kachanov, D Yu; Tereshchenko, G V; Uskova, N G; Merkulov, N N; Semin, K S; Tverdov, I V; Grachev, N S.
Afiliación
  • Akhaladze DG; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Rabaev GS; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Likar YN; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Kireeva ED; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Kachanov DY; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Tereshchenko GV; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Uskova NG; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Merkulov NN; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Semin KS; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Tverdov IV; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
  • Grachev NS; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Khirurgiia (Mosk) ; (12): 27-33, 2021.
Article en En, Ru | MEDLINE | ID: mdl-34941206
OBJECTIVE: To analyze the initial data on future liver remnant volume and its function evaluated by 99mTc-Bromesida hepatobiliary scintigraphy in children with liver tumors. MATERIAL AND METHODS: Extended liver resections were performed in 58 patients aged 2 months - 208 months (median 26 months) for various neoplasms. Before hepatectomy, all children underwent contrast-enhanced CT with volumetry and hepatobiliary scintigraphy with 99mTc-Bromezida and subsequent quantitative assessment of its accumulation in the future liver remnant. All consecutive patients eligible for extended liver resection were retrospectively analyzed. RESULTS: The analysis included patients who underwent extended liver resection between June 2017 and March 2021. Among 91 liver resections, 58 (64%) procedures were extended hepatectomies including 2 ALPPS procedures. Median volume of future liver remnant was 44.5% (16.5-91.4), median future liver remnant function - 10.14%/min/m2 (1.8-30). Four patients with adequate liver function had insufficient volume of future liver remnant. Insufficient future liver remnant volume and its appropriate function were observed in 2 patients. Not life-threatening post-resection liver failure developed in 2 patients. CONCLUSION: Evaluation of future liver remnant function is the most sensitive method to predict post-hepatectomy liver failure in children. The cut off value of future liver remnant volume in children is below 25% and probably below 16.5%. Further data collection and research are warranted to determine significant values. These data will contribute to define the new indications for two-staged hepatectomies in children.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hígado / Neoplasias Hepáticas Tipo de estudio: Observational_studies Límite: Child / Child, preschool / Humans / Infant Idioma: En / Ru Revista: Khirurgiia (Mosk) Año: 2021 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hígado / Neoplasias Hepáticas Tipo de estudio: Observational_studies Límite: Child / Child, preschool / Humans / Infant Idioma: En / Ru Revista: Khirurgiia (Mosk) Año: 2021 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia