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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.
Vos, Joris L; Elbers, Joris B W; Krijgsman, Oscar; Traets, Joleen J H; Qiao, Xiaohang; van der Leun, Anne M; Lubeck, Yoni; Seignette, Iris M; Smit, Laura A; Willems, Stefan M; van den Brekel, Michiel W M; Dirven, Richard; Baris Karakullukcu, M; Karssemakers, Luc; Klop, W Martin C; Lohuis, Peter J F M; Schreuder, Willem H; Smeele, Ludi E; van der Velden, Lilly-Ann; Bing Tan, I; Onderwater, Suzanne; Jasperse, Bas; Vogel, Wouter V; Al-Mamgani, Abrahim; Keijser, Astrid; van der Noort, Vincent; Broeks, Annegien; Hooijberg, Erik; Peeper, Daniel S; Schumacher, Ton N; Blank, Christian U; de Boer, Jan Paul; Haanen, John B A G; Zuur, Charlotte L.
Afiliación
  • Vos JL; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Elbers JBW; Department of Radiation Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Krijgsman O; Neogene Therapeutics, Amsterdam, The Netherlands.
  • Traets JJH; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Qiao X; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van der Leun AM; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Lubeck Y; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Seignette IM; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Smit LA; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Willems SM; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van den Brekel MWM; Department of Pathology and Medical Biology, Groningen University Medical Center, Groningen, The Netherlands.
  • Dirven R; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Baris Karakullukcu M; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Karssemakers L; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Klop WMC; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Lohuis PJFM; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Schreuder WH; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Smeele LE; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van der Velden LA; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Bing Tan I; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Onderwater S; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Jasperse B; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Vogel WV; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Al-Mamgani A; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Keijser A; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • van der Noort V; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Broeks A; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Hooijberg E; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Peeper DS; Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands.
  • Schumacher TN; Department of Otorhinolaryngology Head and Neck Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Blank CU; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • de Boer JP; Department of Radiology, Amsterdam University Medical Center location VUmc, Amsterdam, The Netherlands.
  • Haanen JBAG; Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Zuur CL; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Nat Commun ; 12(1): 7348, 2021 12 22.
Article en En | MEDLINE | ID: mdl-34937871
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Neoadyuvante / Ipilimumab / Carcinoma de Células Escamosas de Cabeza y Cuello / Nivolumab / Neoplasias de Cabeza y Cuello / Inmunoterapia Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Neoadyuvante / Ipilimumab / Carcinoma de Células Escamosas de Cabeza y Cuello / Nivolumab / Neoplasias de Cabeza y Cuello / Inmunoterapia Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido