A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis.

Bojanowski, Krzysztof; Ibeji, Collins U; Singh, Parvesh; Swindell, William R; Chaudhuri, Ratan K

Bojanowski, Krzysztof; Ibeji, Collins U; Singh, Parvesh; Swindell, William R; Chaudhuri, Ratan K.

Afiliación

Bojanowski K; Sunny BioDiscovery, Inc, Santa Paula, California, USA.
Ibeji CU; Symbionyx Pharmaceuticals Inc, Boonton, New Jersey, USA.
Singh P; Department of Pure and Industrial Chemistry, Faculty of Physical Sciences, University of Nigeria, Nsukka, Nigeria.
Swindell WR; School of Chemistry & Physics, University of KwaZulu-Natal, Durban, South Africa.
Chaudhuri RK; Department of Internal Medicine, The Jewish Hospital, Cincinnati, Ohio, USA.

JID Innov ; 1(4): 100040, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34909741

Palabras clave

ARE, antioxidant response element; CES2, carboxylesterase 2; CPD, cyclobutane pyrimidine dimer; CTRL, control; DEG, differentially expressed gene; DMF, dimethyl fumarate; FC, fold change; FDR, false discovery rate; GSH, glutathione; IDMF, isosorbide di-(methyl fumarate); IMQ, imiquimod; KC, keratinocyte; MMF, monomethyl fumarate; PN, uninvolved skin from psoriasis patient; PP, lesional skin from psoriasis patient; RNA-seq, RNA sequencing; VEH, vehicle

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JID Innov Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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