Impact of monomeric and aggregated wild-type and A30P/A53T double-mutant &#945;-synuclein on antioxidant mechanism and glutamate metabolic profile of cultured astrocytes.

Raj, Aishwarya; Kaushal, Alka; Datta, Indrani

Impact of monomeric and aggregated wild-type and A30P/A53T double-mutant α-synuclein on antioxidant mechanism and glutamate metabolic profile of cultured astrocytes.

Raj, Aishwarya; Kaushal, Alka; Datta, Indrani.

Afiliación

Raj A; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India.
Kaushal A; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India.
Datta I; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India.

J Neurosci Res ; 100(2): 681-706, 2022 02.

Article en En | MEDLINE | ID: mdl-34904280

Asunto(s)

Astrocitos; alfa-Sinucleína; Animales; Antioxidantes/metabolismo; Astrocitos/metabolismo; Células Cultivadas; Ácido Glutámico/metabolismo; Metaboloma; Ratas; alfa-Sinucleína/metabolismo

Palabras clave

Nrf2-regulated antioxidants; RRID:SCR_001905; RRID:SCR_002798; RRID:SCR_003070; RRID:SCR_003210; RRID:SCR_013673; astrocytes; extracellular α-synuclein; glutamate uptake and metabolism; glutathione; membrane association/endocytosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Astrocitos / Alfa-Sinucleína Límite: Animals Idioma: En Revista: J Neurosci Res Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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