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Deferral due to low hemoglobin and predictors of permanence in the blood donation system of repeat female blood donors.
Urbina, Adriana; García-Otálora, Michel-Andrés; Mendoza-Romero, Dario; Rocha, Felix; Rodriguez, Ayda; Palomino, Fernando; Weinauer, Franz.
Afiliación
  • Urbina A; Universidad del Rosario, Escuela de Medicina y Ciencias de la Salud, Carrera 24 #63C-69, Quinta Mutis, Bogotá, D.C., Colombia. Electronic address: adriana.urbina@urosario.edu.co.
  • García-Otálora MA; Universidad del Rosario, Escuela de Medicina y Ciencias de la Salud, Carrera 24 #63C-69, Quinta Mutis, Bogotá, D.C., Colombia.
  • Mendoza-Romero D; Fundación Universitaria del Area Andina, Facultad de Ciencias de la Salud y el Deporte, Calle 69 #15-40, Bogotá, Colombia.
  • Rocha F; Banco Nacional de Sangre, Cruz Roja Colombiana, Av Carrera 68 #68B-31, Bogotá, D.C., Colombia.
  • Rodriguez A; Banco Nacional de Sangre, Cruz Roja Colombiana, Av Carrera 68 #68B-31, Bogotá, D.C., Colombia.
  • Palomino F; FUATS, Carrera 70 #120-99, Bogotá, D.C., Colombia.
  • Weinauer F; German RC Blood Services, Working Group of the GRC, Am Mühlberg 14 B Starnberg, D- 82319, Germany.
Transfus Apher Sci ; 61(3): 103340, 2022 Jun.
Article en En | MEDLINE | ID: mdl-34896008
OBJECTIVES: To evaluate the deferral rate due to low hemoglobin (Hb) in repeat female blood donors and identify the factors affecting their permanence in the blood donation system. MATERIALS AND METHODS: 8,368 repeat female blood donors who donated from January 2012 to December 2018 were included. Bivariate analysis and Kaplan-Meier curves were used to identify the covariates possibly associated with developing low Hb, and Cox proportional hazards modeling was used to adjust for all confounders. RESULTS: The global deferral rate due to low Hb was 2.4 %. According to baseline Hb, the frequency of low Hb was 0.7-4.1 %, and it was higher in platelet donors (5.8-9.1 %) than in whole blood donors (1.9 %). The main predictors were baseline Hb (compared to the first quartile; hazard ratio [HR] = 0.487 for the second quartile; 0.234 for the third; and 0.095 for the fourth); change in Hb (HR = 2.689 for a >0.49 g/dL change, compared to smaller changes); the type of donation (compared to whole blood donors, HR = 2.317 for platelet donors); and donation interval (compared to >12.5 month intervals; HR = 2.220 for 8.0-12.5 months; HR = 5.658 for 5.4-8.0 months; and HR = 9.452 for <5.4 months). CONCLUSIONS: In female blood donors at moderate altitude, the probability of developing low Hb increases with a baseline Hb of 13.5-14.0 g/dL, with a change in Hb >0.49 g/dL, in platelet donors, and with donation intervals <12.5 months. These four predictive factors can be used together for early identification of donors at risk of developing low Hb, to institute appropriate measures.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Donantes de Sangre / Hemoglobinas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Transfus Apher Sci Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Donantes de Sangre / Hemoglobinas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Transfus Apher Sci Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido