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Understanding early-life pain and its effects on adult human and animal emotionality: Translational lessons from rodent and zebrafish models.
de Abreu, Murilo S; Giacomini, Ana C V V; Genario, Rafael; Demin, Konstantin A; Amstislavskaya, Tamara G; Costa, Fabiano; Rosemberg, Denis B; Sneddon, Lynne U; Strekalova, Tatyana; Soares, Marta C; Kalueff, Allan V.
Afiliación
  • de Abreu MS; Bioscreening Platform, School of Pharmacy, Southwest University, Chongqing, China; Bioscience Institute, University of Passo Fundo, Passo Fundo, RS, Brazil; Laboratory of Cell and Molecular Biology and Neurobiology, Moscow Institute of Physics and Technology, Moscow, Russia; The International Zebraf
  • Giacomini ACVV; Bioscience Institute, University of Passo Fundo, Passo Fundo, RS, Brazil; Postgraduate Program in Environmental Sciences, University of Passo Fundo, Passo Fundo, RS, Brazil.
  • Genario R; Bioscience Institute, University of Passo Fundo, Passo Fundo, RS, Brazil.
  • Demin KA; Institute of Experimental Medicine, Almazov National Medcial Research Center, Ministry of Healthcare of Russian Federation, St. Petersburg, Russia; Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia; Granov Russian Scientific Research Center of Radiology
  • Amstislavskaya TG; Scientific Research Institute of Neuroscience and Medicine, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia; The International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, LA, USA.
  • Costa F; Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Brazil; Neurobiology Program, Sirius University of Science and Technology, Sochi, Russia.
  • Rosemberg DB; Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Brazil; The International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, LA, USA.
  • Sneddon LU; University of Gothenburg, Department of Biological and Environmental Sciences, Gothenburg, Sweden.
  • Strekalova T; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov 1st Moscow State Medical University, Moscow,
  • Soares MC; CIBIO, Research Centre in Biodiversity and Genetic Resources, University of Porto, Campus Agrário de Vairão, Vairão, Portugal.
  • Kalueff AV; School of Pharmacy, Southwest University, Chongqing, China; Ural Federal University, Ekaterinburg, Russia; Neurobiology Program, Sirius University of Science and Technology, Sochi, Russia. Electronic address: avkalueff@gmail.com.
Neurosci Lett ; 768: 136382, 2022 01 18.
Article en En | MEDLINE | ID: mdl-34861343
Critical for organismal survival, pain evokes strong physiological and behavioral responses in various sentient species. Clinical and preclinical (animal) studies markedly increase our understanding of biological consequences of developmental (early-life) adversity, as well as acute and chronic pain. However, the long-term effects of early-life pain exposure on human and animal emotional responses remain poorly understood. Here, we discuss experimental models of nociception in rodents and zebrafish, and summarize mounting evidence of the role of early-life pain in shaping emotional traits later in life. We also call for further development of animal models to probe the impact of early-life pain exposure on behavioral traits, brain disorders and novel therapeutic treatments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor / Modelos Animales de Enfermedad / Emociones / Investigación Biomédica Traslacional / Experiencias Adversas de la Infancia Límite: Animals / Humans Idioma: En Revista: Neurosci Lett Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor / Modelos Animales de Enfermedad / Emociones / Investigación Biomédica Traslacional / Experiencias Adversas de la Infancia Límite: Animals / Humans Idioma: En Revista: Neurosci Lett Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda