Perfect adaptation of CD8<sup>+</sup> T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation.

Trendel, Nicola; Kruger, Philipp; Gaglione, Stephanie; Nguyen, John; Pettmann, Johannes; Sontag, Eduardo D; Dushek, Omer

Perfect adaptation of CD8⁺ T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation.

Trendel, Nicola; Kruger, Philipp; Gaglione, Stephanie; Nguyen, John; Pettmann, Johannes; Sontag, Eduardo D; Dushek, Omer.

Afiliación

Trendel N; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.
Kruger P; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.
Gaglione S; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.
Nguyen J; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.
Pettmann J; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.
Sontag ED; Radcliffe Department of Medicine, Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, OX1 3RE Oxford, UK.
Dushek O; Electrical and Computer Engineering and Bioengineering, Northeastern University, Boston, MA 02115, USA.

Sci Signal ; 14(666): eaay9363, 2021 01 19.

Article en En | MEDLINE | ID: mdl-34855472

Asunto(s)

Linfocitos T CD8-positivos; Activación de Linfocitos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Activación de Linfocitos / Linfocitos T CD8-positivos Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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