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Systemic diseases and their association with open-angle glaucoma in the population of Stockholm.
Wändell, Per; Carlsson, Axel C; Ljunggren, Gunnar.
Afiliación
  • Wändell P; Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Alfred Nobels Allé 23, 141 83, Huddinge, Sweden. per.wandell@ki.se.
  • Carlsson AC; Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Alfred Nobels Allé 23, 141 83, Huddinge, Sweden.
  • Ljunggren G; Academic Primary Health Care Centre, Region Stockholm Region, Stockholm, Sweden.
Int Ophthalmol ; 42(5): 1481-1489, 2022 May.
Article en En | MEDLINE | ID: mdl-34845599
OBJECTIVE: We aimed to study open-angle glaucoma in association with somatic comorbidities in the total population of adults in Region Stockholm. METHODS: The study population included all living persons aged 19 years and above who resided in Stockholm County, Sweden, on 1 January 2017 (N = 1 703 675). Subjects with specified diseases were identified with data from all registered consultations and hospital stays during 2008-2019. As outcome, the risk of being associated with a diagnosis of open-angle glaucoma was identified during 2012-2018. Analyses were performed by gender, controlling for age and socio-economic status. Age-adjusted odds ratios (ORs) with 95% confidence intervals (95% CI) for women and men with open-angle glaucoma, using individuals without this as referents, were calculated. Socio-economic status was assessed based on the neighbourhood the subjects lived in. RESULTS: In total, 16,299 cases of open-angle glaucoma were identified during 2012-2018, 9204 women and 7095 men. Higher fully adjusted OR (95% CI) for risk of being associated with open-angle glaucoma was for women and men with diabetes 1.138 (1.074-1.207) and 1.216 (1.148-1.289), cancer 1.175 (1.120-1.233) and 1.106 (1.048-1.166), hypertension 1.372 (1.306-1.440) and 1.243 (1.179-1.311); and for women with thyroid diseases 1.086 (1.030-1.146), chronic lung diseases 1.153 (1.093-1.216), and inflammatory arthropathies 1.132 (1.006-1.275). Higher glaucoma incidence was observed in individuals residing in high socio-economic status neighbourhoods. CONCLUSION: The risk of glaucoma is increased in some somatic diseases, especially in individuals with diabetes, hypertension and cancer; and in higher socio-economic neighbourhoods as compared to lower socio-economic neighbourhoods.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glaucoma de Ángulo Abierto / Diabetes Mellitus / Hipertensión / Neoplasias Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Int Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glaucoma de Ángulo Abierto / Diabetes Mellitus / Hipertensión / Neoplasias Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Int Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Países Bajos