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The Hubei Memory and Aging Cohort Study: Study Design, Baseline Characteristics, and Prevalence of Cognitive Impairments.
Li, Lin; Cheng, Gui-Rong; Liu, Dan; Hu, Fei-Fei; Gan, Xu-Guang; Zhang, Bo; An, Lina; Chen, Cong; Zou, Ming-Jun; Xu, Lang; Ou, Yang-Ming; Chen, Yu-Shan; Li, Jin-Quan; Wei, Zhen; Wu, Qiong; Chen, Xing-Xing; Guo, Man-Qing; Wu, Qing-Ming; Wang, Ru; Zeng, Yan.
Afiliación
  • Li L; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Cheng GR; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Liu D; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Hu FF; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Gan XG; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Zhang B; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • An L; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Chen C; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Zou MJ; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Xu L; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Ou YM; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Chen YS; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Li JQ; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Wei Z; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Wu Q; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Chen XX; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Guo MQ; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
  • Wu QM; Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China.
  • Wang R; China Resources and WISCO General Hospital, Wuhan University of Science and Technology, Wuhan, China.
  • Zeng Y; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
J Alzheimers Dis ; 85(2): 561-571, 2022.
Article en En | MEDLINE | ID: mdl-34842190
BACKGROUND: Despite the improved access to health services in China, inadequate diagnosis and management of dementia are common issues, especially in rural regions. OBJECTIVE: The Hubei Memory & Aging Cohort Study was designed as a prospective study in Central China to determine the prevalence, incidence, and risk factors for dementia and mild cognitive impairment (MCI) among urban and rural older adults. METHODS: From 2018-2020, participants aged ≥65 years were screened, and data regarding their life behaviors, families, socio-economic status, physical and mental health, social and psychological factors, and cognition were collected. Diagnoses of MCI and dementia were made via consensus diagnosis using the Diagnostic and Statistical Manual of Mental Disorders fourth edition criteria. RESULTS: Of 8,221 individuals who completed their baseline clinical evaluation, 4,449 (54.1%) were women and 3,164 (38.4%) were from remote rural areas (average age: 71.96 years; mean education period: 7.58 years). At baseline, 25.98%(95%confidence interval [CI]: 24.99-26.96) and 7.24%(95%CI: 6.68-7.80) of the participants were diagnosed with MCI and dementia, respectively. Prevalence showed a strong relationship with age. The substantial disparities between rural and urban regions in MCI and dementia prevalence and multiple dementia-related risk factors were revealed. Especially for dementia, the prevalence rate in rural areas was 2.65 times higher than that in urban regions. CONCLUSION: Our results suggested that public health interventions are urgently needed to achieve equitable diagnosis and management for people living with dementia in the communities across urban and rural areas.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disfunción Cognitiva Tipo de estudio: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disfunción Cognitiva Tipo de estudio: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos