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Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report.
Aminimoghaddam, Soheila; Rahbari, Ali; Pourali, Roghayeh.
Afiliación
  • Aminimoghaddam S; Department of Obstetrics and Gynecology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
  • Rahbari A; Department of Pathology, Jam Hospital, Tehran, Iran.
  • Pourali R; Department of Obstetrics and Gynecology, Jam Hospital, Fajr Street, Motahari Street, 1588657915, Tehran, Iran. Roghayehpourali@ymail.com.
J Med Case Rep ; 15(1): 570, 2021 Nov 28.
Article en En | MEDLINE | ID: mdl-34838127
BACKGROUND: Uterine sarcoma accounts for 3-7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine sarcoma. It is the most common soft tissue malignancy in children while rare in adults. In young patients, the majority of genital tract rhabdomyosarcomas occur in vagina; however, the most common site of gynecologic rhabdomyosarcoma is cervix followed by uterine corpus, in adults. Uterine corpus rhabdomyosarcoma is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. CASE PRESENTATION: Here we report a case of pure rhabdomyosarcoma of uterine corpus in a 60-year-old Iranian postmenopausal female who had osteopetrosis, presenting with 8-month heavy vaginal bleeding and a protruding cervical mass. She is alive on 18-month follow-up after treatment. CONCLUSIONS: Rhabdomyosarcoma of uterine corpus is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. Treatment options in adult gynecological rhabdomyosarcoma are based on studies in younger patients, and more studies may help us choose the best approach for improving outcome.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteopetrosis / Rabdomiosarcoma / Neoplasias Uterinas / Neoplasias del Cuello Uterino / Rabdomiosarcoma Embrionario Tipo de estudio: Prognostic_studies Límite: Adult / Child / Female / Humans / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Med Case Rep Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteopetrosis / Rabdomiosarcoma / Neoplasias Uterinas / Neoplasias del Cuello Uterino / Rabdomiosarcoma Embrionario Tipo de estudio: Prognostic_studies Límite: Adult / Child / Female / Humans / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Med Case Rep Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido