Your browser doesn't support javascript.
loading
Walking down Skeletal Muscle Lane: From Inflammasome to Disease.
Dubuisson, Nicolas; Versele, Romain; Davis-López de Carrizosa, María A; Selvais, Camille M; Brichard, Sonia M; Abou-Samra, Michel.
Afiliación
  • Dubuisson N; Endocrinology, Diabetes and Nutrition Unit, Institute of Experimental and Clinical Research, Medical Sector, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Versele R; Neuromuscular Reference Center, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium.
  • Davis-López de Carrizosa MA; Endocrinology, Diabetes and Nutrition Unit, Institute of Experimental and Clinical Research, Medical Sector, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Selvais CM; Endocrinology, Diabetes and Nutrition Unit, Institute of Experimental and Clinical Research, Medical Sector, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Brichard SM; Departamento de Fisiología, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain.
  • Abou-Samra M; Endocrinology, Diabetes and Nutrition Unit, Institute of Experimental and Clinical Research, Medical Sector, Université Catholique de Louvain, 1200 Brussels, Belgium.
Cells ; 10(11)2021 11 04.
Article en En | MEDLINE | ID: mdl-34831246
Over the last decade, innate immune system receptors and sensors called inflammasomes have been identified to play key pathological roles in the development and progression of numerous diseases. Among them, the nucleotide-binding oligomerization domain (NOD-), leucine-rich repeat (LRR-) and pyrin domain-containing protein 3 (NLRP3) inflammasome is probably the best characterized. To date, NLRP3 has been extensively studied in the heart, where its effects and actions have been broadly documented in numerous cardiovascular diseases. However, little is still known about NLRP3 implications in muscle disorders affecting non-cardiac muscles. In this review, we summarize and present the current knowledge regarding the function of NLRP3 in diseased skeletal muscle, and discuss the potential therapeutic options targeting the NLRP3 inflammasome in muscle disorders.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Músculo Esquelético / Inflamasomas / Enfermedades Musculares Límite: Animals / Humans Idioma: En Revista: Cells Año: 2021 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Músculo Esquelético / Inflamasomas / Enfermedades Musculares Límite: Animals / Humans Idioma: En Revista: Cells Año: 2021 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Suiza