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Deficits of social cognition in bipolar disorder: Systematic review and meta-analysis.
Gillissie, Emily S; Lui, Leanna M W; Ceban, Felicia; Miskowiak, Kamilla; Gok, Sena; Cao, Bing; Teopiz, Kayla M; Ho, Roger; Lee, Yena; Rosenblat, Joshua D; McIntyre, Roger S.
Afiliación
  • Gillissie ES; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Lui LMW; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Ceban F; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Miskowiak K; Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
  • Gok S; Mental Health Services, Capital Region of Denmark, Copenhagen, Denmark.
  • Cao B; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Teopiz KM; Key Laboratory of Cognition and Personality, Faculty of Psychology, Ministry of Education, Southwest University, Chongqing, P. R. China.
  • Ho R; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Lee Y; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Rosenblat JD; Institute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore, Singapore.
  • McIntyre RS; Mood Disorder Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Bipolar Disord ; 24(2): 137-148, 2022 03.
Article en En | MEDLINE | ID: mdl-34825440
BACKGROUND: The association between impaired social cognition and bipolar disorder (BD) is well established. However, to our knowledge, there has not been a recent systematic review that characterizes disparate dimensions of social cognition in BD. Herein, this systematic review and meta-analysis aimed to synthesize the literature on core aspects of social cognition (i.e., Theory of Mind, emotion recognition, and social judgment) to identify potential areas of impairment. METHODS: Online databases (i.e., PubMed, Cochrane Libraries, PsycINFO) and Google Scholar were searched from inception to May 2021. Studies with populations ages ≥16 with DSM-IV or DSM-5 defined BD (I or II) either in a euthymic or symptomatic state were included. The risk of bias was measured using the ROBINS-1 tool, and the quality of the sources was evaluated using GRADE criteria. The results of the studies were quantitatively measured by synthesizing Hedge's g effect sizes through a random effects meta-analytic approach. RESULTS: A total of 29 studies were included in the final review (i.e., 12 studies on the Theory of Mind, 11 on emotion recognition, and 6 on social judgment). Overall, results demonstrated social cognition to be moderately impaired in individuals with BD (d = 0.59). The individual domains ranged in effect size (0.38 < d < 0.70), providing evidence for variation in impairment within social cognition. DISCUSSION: Individuals with BD exhibit clinically significant deficits in social cognition during euthymic and symptomatic states. Social cognition impairments in individuals with BD are an important therapeutic target for treatment discovery and development.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Teoría de la Mente / Disfunción Cognitiva Tipo de estudio: Prognostic_studies / Systematic_reviews Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Bipolar Disord Asunto de la revista: PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Dinamarca
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Teoría de la Mente / Disfunción Cognitiva Tipo de estudio: Prognostic_studies / Systematic_reviews Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Bipolar Disord Asunto de la revista: PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Dinamarca