Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs.
J Mass Spectrom Adv Clin Lab
; 19: 7-19, 2021 Jan.
Article
en En
| MEDLINE
| ID: mdl-34820661
C0, Pre-dose trough concentration; C2, 2-hour post-dose concentration; CS, Calibration standard; CV%, Coefficient of variation; DBS, Dried blood spots; DMPS, Dried matrix on paper discs; Dried matrix on paper discs (DMPD); ESI+, Positive electrospray source ionization mode; Hematocrit; Ht, Hematocrit; ICb95%, 95% confidence interval for intercepts; ICm95%, 95% confidence interval for slopes; Immunosuppressants; LC-MS/MS, Liquid chromatography coupled to tandem mass spectrometry; LLOQ, Lower limit of quantitation; LSS, Limited sampling strategy; Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS); Method comparison; PCDBS, Pre-cut dried blood spots; PDBS, Perforated dried blood spots; PIs, Prediction intervals; QC, Quality control samples; R%, Relative recovery; RE%, Percentage of the relative error; ZnSO4·7H2O, Zinc sulfate heptahydrate; [M+NH4]+, Ammoniated adduct; mTOR, Mechanistic target of Rapamycin
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Guideline
/
Prognostic_studies
Idioma:
En
Revista:
J Mass Spectrom Adv Clin Lab
Año:
2021
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Países Bajos