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Health-related quality of life and disability in adults with juvenile idiopathic arthritis: comparison with adult-onset rheumatic diseases.
Oliveira Ramos, Filipa; Rodrigues, Ana; Magalhaes Martins, Fernando; Melo, Ana Teresa; Aguiar, Francisca; Brites, Luisa; Azevedo, Soraia; Duarte, Ana Catarina; Furtado, Carolina; Mourão, Ana Filipa; Sequeira, Graça; Cunha, Inês; Figueira, Ricardo; Melo Gomes, Jose Antonio; Santos, Maria Jose; Fonseca, Joao Eurico.
Afiliación
  • Oliveira Ramos F; Rheumatology Department and Pediatric Rheumatology Unit, Centro Hospitalar Universitário Lisboa Norte EPE, Lisboa, Portugal filipa.o.ramos@gmail.com.
  • Rodrigues A; Faculdade de Medicina, Universidade de Lisboa Instituto de Medicina Molecular, Lisboa, Portugal.
  • Magalhaes Martins F; Centre for Chronic Diseases (CEDOC), CHRC Campus Nova Medical School, Lisboa, Portugal.
  • Melo AT; Portuguese Society of Rheumatology, Lisboa, Portugal.
  • Aguiar F; Rheumatology Department and Pediatric Rheumatology Unit, Centro Hospitalar Universitário Lisboa Norte EPE, Lisboa, Portugal.
  • Brites L; Young Adult and Pediatric Rheumatology Unit, Centro Hospitalar Universitario de Sao Joao, Porto, Portugal.
  • Azevedo S; Rheumatology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal.
  • Duarte AC; Rheumatology, Unidade Local de Saude do Alto Minho EPE, Viana do Castelo, Portugal.
  • Furtado C; Rheumatology, Hospital Garcia de Orta EPE, Almada, Portugal.
  • Mourão AF; Rheumatology, Hospital do Divino Espírito Santo, São Miguel, Ponta Delgada, Portugal.
  • Sequeira G; Centre for Chronic Diseases (CEDOC), CHRC Campus Nova Medical School, Lisboa, Portugal.
  • Cunha I; Rheumatology, Centro Hospitalar de Lisboa Ocidental EPE, Lisboa, Portugal.
  • Figueira R; Rheumatology, Centro Hospitalar Universitário do Algarve, Faro, Portugal.
  • Melo Gomes JA; Rheumatology, Centro Hospitalar do Baixo Vouga EPE, Aveiro, Portugal.
  • Santos MJ; Rheumatology, Hospital Dr. Nélio Mendonça, Funchal, Madeira, Portugal.
  • Fonseca JE; Instituto Português de Reumatologia, Lisboa, Portugal.
RMD Open ; 7(3)2021 11.
Article en En | MEDLINE | ID: mdl-34819385
OBJECTIVE: To compare physical disability, mental health, fatigue and health-related quality of life (HRQoL) across juvenile idiopathic arthritis (JIA) categories in adulthood and between JIA and adult-onset rheumatic diseases. METHODS: Cross-sectional analysis nested in a cohort of adult patients with JIA registered in the Rheumatic Diseases Portuguese Register (Reuma.pt). Physical disability (Health Assessment Questionnaire-Disability Index), mental health symptoms (Hospital Anxiety and Depression Scale), fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT-F)) and HRQoL (EuroQol-5D (EQ5D) and Short Form (SF-36)) were compared across JIA categories. Patients with polyarticular JIA and enthesis-related arthritis (ERA) JIA were compared respectively to patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA), matched for gender and age, adjusted for disease duration and activity. RESULTS: 585 adult patients with JIA were included. Comparison across JIA categories showed that persistent oligoarthritis and patients with ERA reported a higher score in EQ5D and SF-36 physical component when compared with other JIA categories.Polyarticular JIA reported less disability and fatigue than patients with RA (median Health Assessment Questionnaire of 0.25 vs 0.63; p<0.001 and median FACIT-F score 42 vs 40 ; p=0.041). Polyarticular JIA had also better scores on EQ5D and all domains of SF-36, than patients with RA. Patients with ERA reported less depression and anxiety symptoms (0% vs 14.8%; p=0.003% and 9% vs 21.3%; p=0.002) and less fatigue symptoms (45 vs 41; p=0.01) than patients with SpA. CONCLUSION: Persistent oligoarticular JIA and ERA are the JIA categories in adulthood with better HRQoL. Overall, adult polyarticular and patients with ERA JIA have lower functional impairment and better quality-of-life than patients with RA and SpA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Juvenil / Artritis Reumatoide Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Humans Idioma: En Revista: RMD Open Año: 2021 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Juvenil / Artritis Reumatoide Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Humans Idioma: En Revista: RMD Open Año: 2021 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido