Dissolution/Permeation of Albendazole in the Presence of Cyclodextrin and Bile Salts: A Mechanistic In Vitro Study into Factors Governing Oral Bioavailability.

Eriksen, Jonas Borregaard; Christensen, Stine Bredow; Bauer-Brandl, Annette; Brandl, Martin

Eriksen, Jonas Borregaard; Christensen, Stine Bredow; Bauer-Brandl, Annette; Brandl, Martin.

Afiliación

Eriksen JB; Department of Physics Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark.
Christensen SB; Department of Physics Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark.
Bauer-Brandl A; Department of Physics Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark.
Brandl M; Department of Physics Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark. Electronic address: mmb@sdu.dk.

J Pharm Sci ; 111(6): 1667-1673, 2022 06.

Article en En | MEDLINE | ID: mdl-34808218

Asunto(s)

Ciclodextrinas; 2-Hidroxipropil-beta-Ciclodextrina; Albendazol/química; Ácidos y Sales Biliares; Disponibilidad Biológica; Ciclodextrinas/química; Solubilidad

Palabras clave

Bioavailability; Cyclodextrin(s); Micelle(s); Permeability; Poorly water-soluble drug(s); Solubility; Supersaturation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ciclodextrinas Tipo de estudio: Prognostic_studies Idioma: En Revista: J Pharm Sci Año: 2022 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Estados Unidos

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