Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca<sup>2+</sup> channels at ER-PM junctions.

Vierra, Nicholas C; O'Dwyer, Samantha C; Matsumoto, Collin; Santana, L Fernando; Trimmer, James S

Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca²⁺ channels at ER-PM junctions.

Vierra, Nicholas C; O'Dwyer, Samantha C; Matsumoto, Collin; Santana, L Fernando; Trimmer, James S.

Afiliación

Vierra NC; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, CA 95616.
O'Dwyer SC; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, CA 95616.
Matsumoto C; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, CA 95616.
Santana LF; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, CA 95616.
Trimmer JS; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, CA 95616 jtrimmer@ucdavis.edu.

Proc Natl Acad Sci U S A ; 118(46)2021 11 16.

Article en En | MEDLINE | ID: mdl-34750263

Asunto(s)

Canales de Calcio Tipo L/genética; Membrana Celular/genética; Retículo Endoplásmico/genética; Neuronas/fisiología; Canales de Potasio Shab/genética; Transcripción Genética/genética; Animales; Células Cultivadas; Dendritas/genética; Femenino; Células HEK293; Hipocampo/fisiología; Humanos; Masculino; Ratones; Fosforilación/genética; Ratas

Palabras clave

calcium signaling; excitationtranscription coupling; membrane contact sites; voltage-gated calcium channels; voltage-gated potassium channels

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcripción Genética / Membrana Celular / Canales de Calcio Tipo L / Retículo Endoplásmico / Canales de Potasio Shab / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

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