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Changes in the Antioxidant and Mineral Status of Rabbits After Administration of Dietary Zinc and/or Thyme Extract.
Kucková, Katarína; Gresáková, L'ubomíra; Takácsová, Margaréta; Kandricáková, Anna; Chrastinová, L'ubica; Polaciková, Mária; Cieslak, Adam; Slusarczyk, Sylwester; Cobanová, Klaudia.
Afiliación
  • Kucková K; Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Kosice, Slovakia.
  • Gresáková L; Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Kosice, Slovakia.
  • Takácsová M; Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Kosice, Slovakia.
  • Kandricáková A; Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Kosice, Slovakia.
  • Chrastinová L; National Agricultural and Food Centre, Research Institute for Animal Production, Luzianky, Slovakia.
  • Polaciková M; National Agricultural and Food Centre, Research Institute for Animal Production, Luzianky, Slovakia.
  • Cieslak A; Department of Animal Nutrition, Poznan University of Life Sciences, Poznan, Poland.
  • Slusarczyk S; Department of Pharmaceutical Biology and Botany, Medical University of Wroclaw, Wroclaw, Poland.
  • Cobanová K; Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Kosice, Slovakia.
Front Vet Sci ; 8: 740658, 2021.
Article en En | MEDLINE | ID: mdl-34746281
This study was aimed at determining the impact of organic zinc (Zn) and thyme extract (TE) administration, given alone or together for 6 weeks, on the antioxidant and mineral status (Zn, Cu, Fe, and Mn) in the plasma and tissues of growing rabbits. A total of 96 rabbits of age 35 days were randomly assigned to one of four treatment groups: a control group (C), a Zn group supplemented with dietary zinc (50 mg/kg), a TE group receiving thyme extract applied in drinking water (1 ml/L), and a Zn + TE group treated with both additives. Lipid peroxidation in the plasma was influenced by Zn intake and in the kidney was affected by both the Zn and TE treatment (P < 0.05). Zn supplementation led to a significant increase in glutathione peroxidase activity (P = 0.017), total antioxidant capacity (P = 0.009) and total thiol groups level (P = 0.047) in the kidney, with the highest values occurring in rabbits receiving the combination Zn + TE. Administration of TE influenced Zn content in the kidney (P < 0.001), while zinc intake decreased Cu concentration in muscle (P = 0.021). In conclusion, the simultaneous administration of organic Zn and TE positively affected the antioxidant response of kidneys and can be used for improving the antioxidant status of growing rabbits.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Vet Sci Año: 2021 Tipo del documento: Article País de afiliación: Eslovaquia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Vet Sci Año: 2021 Tipo del documento: Article País de afiliación: Eslovaquia Pais de publicación: Suiza