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In-Stent Restenosis in Saphenous Vein Grafts (from the DIVA Trial).
Xenogiannis, Iosif; Rangan, Bavana V; Uyeda, Lauren; Banerjee, Subhash; Edson, Robert; Bhatt, Deepak L; Goldman, Steven; Holmes, David R; Rao, Sunil V; Shunk, Kendrick; Mavromatis, Kreton; Ramanathan, Kodangudi; Bavry, Antony A; McFalls, Edward O; Garcia, Santiago; Thai, Hoang; Uretsky, Barry F; Latif, Faisal; Armstrong, Ehrin; Ortiz, Jose; Jneid, Hani; Liu, Jayson; Aggrawal, Kul; Conner, Todd A; Wagner, Todd; Karacsonyi, Judit; Ventura, Beverly; Alsleben, Aaron; Lu, Ying; Shih, Mei-Chiung; Brilakis, Emmanouil S.
Afiliación
  • Xenogiannis I; Minneapolis Heart Institute, Abbott Northwestern Hospital Minneapolis, Minnesota.
  • Rangan BV; Minneapolis Heart Institute, Abbott Northwestern Hospital Minneapolis, Minnesota.
  • Uyeda L; Palo Alto Cooperative Studies Program Coordinating Center, Palo Alto, California.
  • Banerjee S; VA North Texas Health Care System and University of Texas Southwestern Medical Center, Dallas, Texas.
  • Edson R; Palo Alto Cooperative Studies Program Coordinating Center, Palo Alto, California.
  • Bhatt DL; Harvard Medical School, Boston, Massachusetts.
  • Goldman S; Sarver Heart Center, Tucson, Arizona.
  • Holmes DR; Mayo Clinic School of Graduate Medical Education, Rochester, Minnesota.
  • Rao SV; Durham Veteran Affairs Medical Center, Durham, North Carolina.
  • Shunk K; San Francisco Veteran Affairs Medical Center, San Francisco, California.
  • Mavromatis K; Atlanta Veteran Affairs Medical Center, Decatur, Georgia.
  • Ramanathan K; Memphis Veteran Affairs Medical Center, Memphis, Tennessee.
  • Bavry AA; North Florida/South Georgia Veterans Health System, Gainesville, Florida.
  • McFalls EO; Minneapolis Veteran Affairs Medical Center, Minneapolis, Minnesota.
  • Garcia S; Minneapolis Heart Institute, Abbott Northwestern Hospital Minneapolis, Minnesota; Minneapolis Veteran Affairs Medical Center, Minneapolis, Minnesota.
  • Thai H; Desert Cardiology of Tucson, Tucson, Arizona.
  • Uretsky BF; John L. McClellan Memorial Veteran Affairs Medical Center, Little Rock, Arkansas.
  • Latif F; Oklahoma City VA Medical Center, Oklahoma City, Oklahoma.
  • Armstrong E; Denver VA Medical Center, Denver, Colorado.
  • Ortiz J; Louis Stokes Cleveland Veteran Affairs Medical Center, Cleveland, Ohio.
  • Jneid H; Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas.
  • Liu J; Hines/North Chicago Veteran Affairs Medical Center, Hines, Illinois.
  • Aggrawal K; Harry S. Truman Memorial VA Medical Center, Columbia, Missouri.
  • Conner TA; Veteran Affairs Cooperative Studies Program Clinical Research Pharmacy, Albuquerque, New Mexico.
  • Wagner T; Health Economics Resource Center, VA Palo Alto, California.
  • Karacsonyi J; VA North Texas Health Care System and University of Texas Southwestern Medical Center, Dallas, Texas; Division of Invasive Cardiology, Second Department of Internal Medicine and Cardiology Center, University of Szeged, Szeged, Hungary.
  • Ventura B; Palo Alto Cooperative Studies Program Coordinating Center, Palo Alto, California.
  • Alsleben A; Palo Alto Cooperative Studies Program Coordinating Center, Palo Alto, California.
  • Lu Y; Department of Health Research and Policy, Stanford University, Stanford, California.
  • Shih MC; Palo Alto Cooperative Studies Program Coordinating Center, Palo Alto, California.
  • Brilakis ES; Minneapolis Heart Institute, Abbott Northwestern Hospital Minneapolis, Minnesota. Electronic address: esbrilakis@gmail.com.
Am J Cardiol ; 162: 24-30, 2022 01 01.
Article en En | MEDLINE | ID: mdl-34736721
Saphenous vein grafts (SVGs) have high rates of in-stent restenosis (ISR). We compared the baseline clinical and angiographic characteristics of patients and lesions that did develop ISR with those who did not develop ISR during a median follow-up of 2.7 years in the DIVA study (NCT01121224). We also examined the ISR types using the Mehran classification. ISR developed in 119 out of the 575 DIVA patients (21%), with similar incidence among patients with drug-eluting stents and bare-metal stents (BMS) (21% vs 21%, p = 0.957). Patients in the ISR group were younger (67 ± 7 vs 69 ± 8 years, p = 0.04) and less likely to have heart failure (27% vs 38%, p = 0.03) and SVG lesions with Thrombolysis In Myocardial Infarction 3 flow before the intervention (77% vs 83%, p <0.01), but had a higher number of target SVG lesions (1.33 ± 0.64 vs 1.16 ± 0.42, p <0.01), more stents implanted in the target SVG lesions (1.52 ± 0.80 vs 1.31 ± 0.66, p <0.01), and longer total stent length (31.37 ± 22.11 vs 25.64 ± 17.42 mm, p = 0.01). The incidence of diffuse ISR was similar in patients who received drug-eluting-stents and BMS (57% vs 54%, p = 0.94), but BMS patients were more likely to develop occlusive restenosis (17% vs 33%, p = 0.05).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Safena / Enfermedad de la Arteria Coronaria / Puente de Arteria Coronaria / Reestenosis Coronaria / Stents Liberadores de Fármacos / Oclusión de Injerto Vascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Cardiol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Safena / Enfermedad de la Arteria Coronaria / Puente de Arteria Coronaria / Reestenosis Coronaria / Stents Liberadores de Fármacos / Oclusión de Injerto Vascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Cardiol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos