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Clinical and Infection Prevention Applications of Severe Acute Respiratory Syndrome Coronavirus 2 Genotyping: An Infectious Diseases Society of America/American Society for Microbiology Consensus Review Document.
Greninger, Alexander L; Dien Bard, Jennifer; Colgrove, Robert C; Graf, Erin H; Hanson, Kimberly E; Hayden, Mary K; Humphries, Romney M; Lowe, Christopher F; Miller, Melissa B; Pillai, Dylan R; Rhoads, Daniel D; Yao, Joseph D; Lee, Francesca M.
Afiliación
  • Greninger AL; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Dien Bard J; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
  • Colgrove RC; Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
  • Graf EH; Division of Infectious Diseases, Mount Auburn Hospital, Harvard School of Medicine, Cambridge, Massachusetts, USA.
  • Hanson KE; Department of Laboratory Medicine and Pathology, Mayo Clinic, Arizona, USA.
  • Hayden MK; Departments of Internal Medicine and Pathology, University of Utah, Salt Lake City, Utah, USA.
  • Humphries RM; Division of Infectious Diseases, Department of Medicine and Division of Laboratory Medicine, Department of Pathology, Rush University Medical Center, Chicago, Illinois, USA.
  • Lowe CF; Division of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Miller MB; Division of Medical Microbiology and Virology, Providence Health Care, Vancouver, British Columbia, Canada.
  • Pillai DR; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Rhoads DD; Clinical Microbiology Laboratory, University of North Carolina Hospitals, Chapel Hill, North Carolina, USA.
  • Yao JD; Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
  • Lee FM; Departments of Pathology and Laboratory Medicine and Microbiology & Infectious Diseases, University of Calgary, Alberta, Canada.
Clin Infect Dis ; 74(8): 1496-1502, 2022 04 28.
Article en En | MEDLINE | ID: mdl-34731234
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged into a world of maturing pathogen genomics, with >2 million genomes sequenced at this writing. The rise of more transmissible variants of concern that affect vaccine and therapeutic effectiveness has led to widespread interest in SARS-CoV-2 evolution. Clinicians are also eager to take advantage of the information provided by SARS-CoV-2 genotyping beyond surveillance purposes. Here, we review the potential role of SARS-CoV-2 genotyping in clinical care. The review covers clinical use cases for SARS-CoV-2 genotyping, methods of SARS-CoV-2 genotyping, assay validation and regulatory requirements, clinical reporting for laboratories, and emerging issues in clinical SARS-CoV-2 sequencing. While clinical uses of SARS-CoV-2 genotyping are currently limited, rapid technological change along with a growing ability to interpret variants in real time foretell a growing role for SARS-CoV-2 genotyping in clinical care as continuing data emerge on vaccine and therapeutic efficacy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / COVID-19 Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / COVID-19 Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos