Modeling the impact of vaccination strategies for nursing homes in the context of increased SARS-CoV-2 community transmission and variants.

Holmdahl, Inga; Kahn, Rebecca; Slifka, Kara Jacobs; Dooling, Kathleen; Slayton, Rachel B

Holmdahl, Inga; Kahn, Rebecca; Slifka, Kara Jacobs; Dooling, Kathleen; Slayton, Rachel B.

Afiliación

Holmdahl I; Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Kahn R; Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Slifka KJ; COVID-19 Response, US Centers for Disease Control and Prevention, Atlanta, Georgia.
Dooling K; COVID-19 Response, US Centers for Disease Control and Prevention, Atlanta, Georgia.
Slayton RB; COVID-19 Response, US Centers for Disease Control and Prevention, Atlanta, Georgia.

medRxiv ; 2021 Oct 26.

Article en En | MEDLINE | ID: mdl-34729570

RESUMEN

Nursing homes (NH) were among the first settings to receive COVID-19 vaccines in the United States, but staff vaccination coverage remains low at an average of 64%. Using an agent-based model, we examined the impact of community prevalence, the Delta variant, staff vaccination coverage, and boosters for residents on outbreak dynamics in nursing homes. We found that increased staff primary series coverage and high booster vaccine effectiveness (VE) in residents leads to fewer infections and that the cumulative incidence is highly dependent on community transmission. Despite high VE, high community transmission resulted in continued symptomatic infections in NHs.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: MedRxiv Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

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