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Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.
Cunha, Luis Eduardo R; Stolet, Adilson A; Strauch, Marcelo A; Pereira, Victor A R; Dumard, Carlos H; Gomes, Andre M O; Monteiro, Fábio L; Higa, Luiza M; Souza, Patrícia N C; Fonseca, Juliana G; Pontes, Francisco E; Meirelles, Leonardo G R; Albuquerque, José W M; Sacramento, Carolina Q; Fintelman-Rodrigues, Natalia; Lima, Tulio M; Alvim, Renata G F; Marsili, Federico F; Caldeira, Marcella Moreira; Zingali, Russolina B; de Oliveira, Guilherme A P; Souza, Thiago M L; Silva, Alexandre S; Muller, Rodrigo; Rodrigues, Daniela Del Rosário Flores; Jesus da Costa, Luciana; Alves, Arthur Daniel R; Pinto, Marcelo Alves; Oliveira, Andréa C; Guedes, Herbert L M; Tanuri, Amilcar; Castilho, Leda R; Silva, Jerson L.
Afiliación
  • Cunha LER; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Stolet AA; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Strauch MA; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Pereira VAR; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Dumard CH; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Gomes AMO; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Monteiro FL; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Higa LM; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Souza PNC; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Fonseca JG; Institute of Biology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Pontes FE; Institute of Biology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Meirelles LGR; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Albuquerque JWM; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Sacramento CQ; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Fintelman-Rodrigues N; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Lima TM; Vital Brazil Institute, Niterói, RJ 24230-410, Brazil.
  • Alvim RGF; Immunopharmacology Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ 21040-900, Brazil.
  • Marsili FF; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, RJ 21040-900, Brazil.
  • Caldeira MM; Immunopharmacology Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ 21040-900, Brazil.
  • Zingali RB; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, RJ 21040-900, Brazil.
  • de Oliveira GAP; Cell Culture Engineering Laboratory, COPPE, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-598, Brazil.
  • Souza TML; Cell Culture Engineering Laboratory, COPPE, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-598, Brazil.
  • Silva AS; Cell Culture Engineering Laboratory, COPPE, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-598, Brazil.
  • Muller R; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Rodrigues DDRF; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Jesus da Costa L; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Alves ADR; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Pinto MA; Institute of Medical Biochemistry Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Oliveira AC; National Institute of Science and Technology for Structural Biology and Bioimaging, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-901, Brazil.
  • Guedes HLM; Immunopharmacology Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ 21040-900, Brazil.
  • Tanuri A; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, RJ 21040-900, Brazil.
  • Castilho LR; Laboratory of Technological Development in Virology (LADTV), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ 21040-900, Brazil.
  • Silva JL; Animal Experimentation Laboratory (LAEAN), Institute of Technology in Immunobiologicals, Bio-Manguinhos, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ 21040-900, Brazil.
iScience ; 24(11): 103315, 2021 Nov 19.
Article en En | MEDLINE | ID: mdl-34723156
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IScience Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IScience Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos