A Novel Statin Compound from Monacolin J Produced Using CYP102A1-Catalyzed Regioselective C-Hydroxylation.

Cao, Ngoc Tan; Nguyen, Ngoc Anh; Park, Chan Mi; Cha, Gun Su; Park, Ki Deok; Yun, Chul-Ho

Cao, Ngoc Tan; Nguyen, Ngoc Anh; Park, Chan Mi; Cha, Gun Su; Park, Ki Deok; Yun, Chul-Ho.

Afiliación

Cao NT; School of Biological Sciences and Biotechnology, Graduate School, Chonnam National University, Yongbong-ro 77, Gwangju 61186, Korea.
Nguyen NA; School of Biological Sciences and Technology, Chonnam National University, Yongbong-ro 77, Gwangju 61186, Korea.
Park CM; School of Biological Sciences and Technology, Chonnam National University, Yongbong-ro 77, Gwangju 61186, Korea.
Cha GS; Namhae Garlic Research Institute, 2465-8 Namhaedaero, Gyungnam 52430, Korea.
Park KD; Gwangju Center, Korea Basic Science Institute, Gwangju 61186, Korea.
Yun CH; School of Biological Sciences and Biotechnology, Graduate School, Chonnam National University, Yongbong-ro 77, Gwangju 61186, Korea.

Pharmaceuticals (Basel) ; 14(10)2021 Sep 26.

Article en En | MEDLINE | ID: mdl-34681205

Palabras clave

HMG-CoA reductase; human liver microsomes; monacolin J; regioselective hydroxylation; statin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2021 Tipo del documento: Article Pais de publicación: Suiza

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