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D-dimer levels for Risk Stratification in Patients with Suspected COVID-19 - A Prospective Observational Study.
Jauslin, A S; Kellett, J; Brabrand, M; Simon, N R; Rueegg, M; Twerenbold, R; Osswald, S; Bassetti, S; Tschudin-Sutter, S; Siegemund, M; Rentsch, K; Bingisser, R; Nickel, C H.
Afiliación
  • Jauslin AS; MD, Emergency Department, University Hospital Basel, 4031 Basel, Switzerland.
  • Kellett J; MD, Department of Emergency Medicine, Hospital of South West Jutland, 6700 Esbjerg, Denmark.
  • Brabrand M; MD, PhD, Department of Emergency Medicine, Hospital of South West Jutland, 6700 Esbjerg, Denmark.
  • Simon NR; MD, Emergency Department, University Hospital Basel, 4031 Basel, Switzerland.
  • Rueegg M; MD, Emergency Department, University Hospital Basel, 4031 Basel, Switzerland.
  • Twerenbold R; MD, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland.
  • Osswald S; MD, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland.
  • Bassetti S; MD, Department of Internal Medicine, University Hospital Basel, 4031 Basel, Switzerland.
  • Tschudin-Sutter S; MD, Division of Infectious Disease & Hospital Epidemiology, University Hospital Basel, 4031 Basel, Switzerland.
  • Siegemund M; MD, Department of Intensive Care, University Hospital Basel, 4031 Basel, Switzerland.
  • Rentsch K; PhD, Department of Laboratory Medicine, University Hospital Basel, 4031 Basel, Switzerland.
  • Bingisser R; MD, Emergency Department, University Hospital Basel, 4031 Basel, Switzerland.
  • Nickel CH; MD, Emergency Department, University Hospital Basel, 4031 Basel, Switzerland.
Acute Med ; 20(3): 193-203, 2021.
Article en En | MEDLINE | ID: mdl-34679137
BACKGROUND: Elevated D-dimer levels have been observed in COVID-19 and are of prognostic value, but have not been compared to an appropriate control group. METHODS: Observational cohort study including emergency patients with suspected or confirmed COVID-19. Logistic regression defined the association of D-dimer levels, COVID-19 positivity, age, and gender with 30-day-mortality. RESULTS: 953 consecutive patients (median age 58, 43% women) presented with suspected COVID-19: 12 (7.4%) patients with confirmed SARS-CoV-2-infection died, compared with 28 (3.5%) patients without SARS-CoV-2-infection. Overall, most (56%) patients had elevated D-dimer levels (≥0.5mg/l). Age (OR 1.07, CI 1.05-1.10), D-dimer levels ≥0.5mg/l (OR 2.44, CI 0.98-7.39), and COVID-19 (OR 2.79, CI 1.28-5.80) were associated with 30-day-mortality. CONCLUSION: D-dimer levels are effective prognosticators in both patient groups.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Acute Med Año: 2021 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Acute Med Año: 2021 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido