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Myocarditis-induced Sudden Death after BNT162b2 mRNA COVID-19 Vaccination in Korea: Case Report Focusing on Histopathological Findings.
Choi, Sangjoon; Lee, SangHan; Seo, Jeong-Wook; Kim, Min-Ju; Jeon, Yo Han; Park, Ji Hyun; Lee, Jong Kyu; Yeo, Nam Seok.
Afiliación
  • Choi S; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
  • Lee S; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea. sanghan111@gmail.com.
  • Seo JW; Department of Pathology, Incheon Sejong Hospital, Incheon, Korea.
  • Kim MJ; Department of Pathology, Incheon Sejong Hospital, Incheon, Korea.
  • Jeon YH; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
  • Park JH; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
  • Lee JK; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
  • Yeo NS; Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
J Korean Med Sci ; 36(40): e286, 2021 Oct 18.
Article en En | MEDLINE | ID: mdl-34664804
We present autopsy findings of a 22-year-old man who developed chest pain 5 days after the first dose of the BNT162b2 mRNA vaccine and died 7 hours later. Histological examination of the heart revealed isolated atrial myocarditis, with neutrophil and histiocyte predominance. Immunohistochemical C4d staining revealed scattered single-cell necrosis of myocytes which was not accompanied by inflammatory infiltrates. Extensive contraction band necrosis was observed in the atria and ventricles. There was no evidence of microthrombosis or infection in the heart and other organs. The primary cause of death was determined to be myocarditis, causally-associated with the BNT162b2 vaccine.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunación / Muerte Súbita / Vacunas contra la COVID-19 / Miocarditis Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: J Korean Med Sci Asunto de la revista: MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Corea del Sur
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunación / Muerte Súbita / Vacunas contra la COVID-19 / Miocarditis Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: J Korean Med Sci Asunto de la revista: MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Corea del Sur