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Stigma, Social Support, Illicit Drug Use, and Other Predictors of Anxiety and Depression Among HIV/AIDS Patients in Pakistan: A Cross-Sectional Study.
Ahmed, Ali; Saqlain, Muhammad; Umair, Malik Muhammad; Hashmi, Furqan Khurshid; Saeed, Hamid; Amer, Muhammad; Blebil, Ali Qais; Dujaili, Juman Abdulelah.
Afiliación
  • Ahmed A; School of Pharmacy, Monash University, Subang Jaya, Malaysia.
  • Saqlain M; Department of Pharmacy, Quaid i Azam University Islamabad, Islamabad, Pakistan.
  • Umair MM; National AIDs Control Program, Prime Minister Health Complex, Islamabad, Pakistan.
  • Hashmi FK; University College of Pharmacy, University of the Punjab, Allama Iqbal, Lahore, Pakistan.
  • Saeed H; University College of Pharmacy, University of the Punjab, Allama Iqbal, Lahore, Pakistan.
  • Amer M; Department of Pharmacy, The University of Lahore, Islamabad, Pakistan.
  • Blebil AQ; School of Pharmacy, Monash University, Subang Jaya, Malaysia.
  • Dujaili JA; School of Pharmacy, Monash University, Subang Jaya, Malaysia.
Front Public Health ; 9: 745545, 2021.
Article en En | MEDLINE | ID: mdl-34660521
Introduction: Anxiety and depression in people living with HIV/AIDS (PLWHA) can lead to non-adherence to antiretroviral therapy (ART), morbidity, and mortality. Therefore, assessing the stigma, social support, and other determinants of anxiety and depression in PLWHA are important for developing further interventions. Methods: An institution-based cross-sectional study was conducted in 505 PLWHA, approached through systematic sampling, who paid routine visits to the ART center, Pakistan Institute of Medical Sciences (PIMS), Islamabad. Data was collected by pretested validated hospital anxiety and depression scale (HADS). Version 26 of the SPSS was used to apply Logistic regression analysis to identify determinants, and the 95% confidence interval (CI) adjusted odds ratio (AOR) was calculated to assess the magnitude of the relationships. Results: In PLWHA, the prevalence of co-morbid depression and anxiety was 80%. Separately, 89.9% had depression, and 80.3% had anxiety. Use of illicit drugs [AOR = 1.87, 95% CI (1.01, 3.27)], low social support [AOR = 1.21, 95% CI (1.02, 2.25)], being male [AOR = 2.21, 95% CI (1.11, 5.49)], and HIV related stigma [AOR = 2.48, 95% CI (1.25, 6.02)] were significant predictors of depression. Having detectable viral load [AOR = 3.04, 95% CI (1.04, 8.86)], young age [AOR = 5.31, 95% CI (1.19, 29.39)], no formal education [AOR = 21.78, 95% CI (4.03, 117.62)], low [AOR = 1.70, 95% CI (1.12, 6.93)] or moderate [AOR = 2.20, 95% CI (1.79, 6.09)] social support, illicit drugs addiction [AOR = 1.17, 95% CI (1.03, 2.55)], and HIV stigma [AOR = 54.3, 95% CI (21.20, 139.32)] had a remarkable association with anxiety. Conclusions: Given the high prevalence of anxiety and depression among PLWHA, the Pakistan Ministry of Health should focus more on monitoring mental health, expanding mental health services, and developing interventions based on identified factors to treat depression and anxiety among PLWHA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Infecciones por VIH / Depresión Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: Front Public Health Año: 2021 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Infecciones por VIH / Depresión Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: Front Public Health Año: 2021 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Suiza