Contemporary dose-escalation methods for early phase studies in the immunotherapeutics era.

Araujo, Daniel V; Oliva, Marc; Li, Kecheng; Fazelzad, Rouhi; Liu, Zhihui Amy; Siu, Lillian L

Araujo, Daniel V; Oliva, Marc; Li, Kecheng; Fazelzad, Rouhi; Liu, Zhihui Amy; Siu, Lillian L.

Afiliación

Araujo DV; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada; Department of Medical Oncology, Hospital de Base, São José Do Rio Preto, SP, Brazil.
Oliva M; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada; Department of Medical Oncology, Institut Catala d' Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Li K; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Fazelzad R; Library and Information Services, University Health Network, Toronto, ON, Canada.
Liu ZA; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Siu LL; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada. Electronic address: lillian.siu@uhn.ca.

Eur J Cancer ; 158: 85-98, 2021 Oct 14.

Article en En | MEDLINE | ID: mdl-34656816

Palabras clave

Dose-escalation methods; Immunotherapeutics; Model-assisted designs; Phase I trials

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Eur J Cancer Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido

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