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Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1ß Secretion in Human Macrophages.
Diaz-Del-Olmo, Ines; Worboys, Jonathan; Martin-Sanchez, Fatima; Gritsenko, Anna; Ambrose, Ashley R; Tannahill, Gillian M; Nichols, Eva-Maria; Lopez-Castejon, Gloria; Davis, Daniel M.
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  • Diaz-Del-Olmo I; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Worboys J; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Martin-Sanchez F; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Gritsenko A; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Ambrose AR; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Tannahill GM; Adaptive Immunity Research Unit, GSK, Stevenage, United Kingdom.
  • Nichols EM; Adaptive Immunity Research Unit, GSK, Stevenage, United Kingdom.
  • Lopez-Castejon G; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
  • Davis DM; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.
Front Immunol ; 12: 720655, 2021.
Article en En | MEDLINE | ID: mdl-34650553
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complejo de Ataque a Membrana del Sistema Complemento / Interleucina-1beta / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Macrófagos Límite: Humans Idioma: En Revista: Front Immunol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complejo de Ataque a Membrana del Sistema Complemento / Interleucina-1beta / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Macrófagos Límite: Humans Idioma: En Revista: Front Immunol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza