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Neurocognitive function following out-of-hospital cardiac arrest: A systematic review.
Zook, Nancy; Voss, Sarah; Blennow Nordström, Erik; Brett, Stephen J; Jenkinson, Elizabeth; Shaw, Pauline; White, Paul; Benger, Jonathan.
Afiliación
  • Zook N; Health and Applied Sciences, University of the West of England, Bristol, UK. Electronic address: nancy.zook@uwe.ac.uk.
  • Voss S; Health and Applied Sciences, University of the West of England, Bristol, UK.
  • Blennow Nordström E; Lund University, Skane University Hospital, Department of Clinical Sciences Lund, Neurology, Lund, Sweden.
  • Brett SJ; Department of Surgery and Cancer, Imperial College London, London, UK.
  • Jenkinson E; Health and Applied Sciences, University of the West of England, Bristol, UK.
  • Shaw P; Health and Applied Sciences, University of the West of England, Bristol, UK.
  • White P; Health and Applied Sciences, University of the West of England, Bristol, UK.
  • Benger J; Health and Applied Sciences, University of the West of England, Bristol, UK.
Resuscitation ; 170: 238-246, 2022 Jan.
Article en En | MEDLINE | ID: mdl-34648921
OBJECTIVES: The primary aim of this review was to investigate neurocognitive outcomes following out-of-hospital cardiac arrest (OHCA). Specifically, the focus was on identifying the different neurocognitive domains that are assessed, the measures used, and the level of, and criteria for, impairment. DESIGN AND REVIEW METHODS: A systematic review of the literature from 2006 to 2021 was completed using Medline, Cinahl and Psychinfo. Criteria for inclusion were studies with participants over the age of 18, OHCA and at least one neurocognitive function measure. Qualitative and case studies were excluded. Reviewers assessed criteria and risk of bias using a modified version of Downs and Black. RESULTS: Forty-three studies were identified. Most studies had a low risk of bias (n = 31) or moderate risk of bias (n = 11) and one had a high risk; however, only six reported effect sizes or power analyses. Multiple measures of neurocognitive outcomes were used (>50) and level of impairment criteria varied considerably. Memory impairments were frequently found and were also more likely to be impaired followed by executive function and processing speed. DISCUSSION: This review highlights the heterogeneity of measures and approaches used to assess neurocognitive outcomes following OHCA as well as the need to improve risk of bias concerning generalizability. Improved understanding of the approaches used for assessment and the subsequent findings will facilitate a standardized evaluation of neurocognitive outcomes following OHCA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Paro Cardíaco Extrahospitalario Tipo de estudio: Prognostic_studies / Qualitative_research / Systematic_reviews Límite: Adult / Humans / Middle aged Idioma: En Revista: Resuscitation Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Paro Cardíaco Extrahospitalario Tipo de estudio: Prognostic_studies / Qualitative_research / Systematic_reviews Límite: Adult / Humans / Middle aged Idioma: En Revista: Resuscitation Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda