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Pachychoroid disease spectrum: review article.
Mazzeo, Thiago José Muniz Machado; Leber, Henrique Monteiro; da Silva, Allan Gomes; Freire, Raimunda Cristina Mendonça; Barbosa, Gabriel Castilho Sandoval; Criado, Guilherme Garcia; Jacob, Gabriel Almeida Veiga; Machado, Cleide Guimarães; Gomes, André Marcelo Vieira.
Afiliación
  • Mazzeo TJMM; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil. mazzeothiago@yahoo.com.
  • Leber HM; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • da Silva AG; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • Freire RCM; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • Barbosa GCS; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • Criado GG; Retina and Vitreous Department, University of São Paulo (USP), São Paulo, Brazil.
  • Jacob GAV; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • Machado CG; Retina and Vitreous Department, Suel Abujamra Institute, São Paulo, Brazil.
  • Gomes AMV; Retina and Vitreous Department, University of São Paulo (USP), São Paulo, Brazil.
Graefes Arch Clin Exp Ophthalmol ; 260(3): 723-735, 2022 Mar.
Article en En | MEDLINE | ID: mdl-34648069
PURPOSE: The aim of this article is to do a comprehensive literature review about the current understandings of the pachychoroid disease spectrum, describing its multimodal imaging analysis, pathophysiology, differential diagnosis, and current types of management. METHODS: This comprehensive literature review was performed based on a search on the PubMed database, of relevant pachychoroid published papers according to our current knowledge. DISCUSSION: The pachychoroid disease spectrum, according to some authors, includes the following: pachychoroid pigment epitheliopathy (PPE), central serous chorioretinopathy (CSC), pachychoroid neovasculopathy (PNV), polypoidal choroidal vasculopathy (PCV)/aneurysmal type 1 neovascularization (AT1), and more recently focal choroidal excavation (FCE) and peripapillary pachychoroid syndrome (PPS). Each one of these entities will be described and discussed in this article. CONCLUSION: Significant advances in multimodal imaging have enabled a better understanding of the typical choroidal changes in pachychoroid disease spectrum. The clinical knowledge and managing options about this disease significantly increased in the last years. However, it is still unclear why some eyes with typical pachychoroid disease phenotype show no evidence of RPE damage and subretinal fluid (uncomplicated pachychoroid) while others present progressive tissue damage, neovascularization, and atrophy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Coroides / Coriorretinopatía Serosa Central Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Humans Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Coroides / Coriorretinopatía Serosa Central Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Humans Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Alemania