Your browser doesn't support javascript.
loading
Norfloxacin and gentamicin degradation catalyzed by manganese porphyrins under mild conditions: the importance of toxicity assessment.
de Souza Santos, Lucilaine Valéria; Lebron, Yuri Abner Rocha; Moreira, Victor Rezende; Jacob, Raquel Sampaio; Martins, Dayse Carvalho da Silva; Lange, Lisete Celina.
Afiliación
  • de Souza Santos LV; Department of Sanitary and Environmental Engineering, Universidade Federal de Minas Gerais, P.O. Box 1294, Belo Horizonte, MG, 30270-901, Brazil. lucilainevaleria@yahoo.com.br.
  • Lebron YAR; Department of Chemical Engineering, Pontifícia Universidade Católica de Minas Gerais, P.O. Box 1686, Belo Horizonte, MG, 30535-901, Brazil. lucilainevaleria@yahoo.com.br.
  • Moreira VR; Department of Sanitary and Environmental Engineering, Universidade Federal de Minas Gerais, P.O. Box 1294, Belo Horizonte, MG, 30270-901, Brazil.
  • Jacob RS; Department of Sanitary and Environmental Engineering, Universidade Federal de Minas Gerais, P.O. Box 1294, Belo Horizonte, MG, 30270-901, Brazil.
  • Martins DCDS; Department of Civil Engineering, Pontifícia Universidade Católica de Minas Gerais, P.O. Box 1686, Belo Horizonte, MG, 30535-901, Brazil.
  • Lange LC; Department of Chemistry, Universidade Federal de Minas Gerais, P.O. Box 1294, Belo Horizonte, MG, 30270-901, Brazil.
Environ Sci Pollut Res Int ; 29(11): 16203-16212, 2022 Mar.
Article en En | MEDLINE | ID: mdl-34647211
The current work assessed the degradation degree and the degradation products derived from norfloxacin (NOR) and gentamicin (GEN) using iodosylbenzene and iodobenzene diacetate, in the presence of manganese porphyrin as catalysts. Better results for NOR degradation (> 80%) were obtained when more hydrophobic porphyrins were employed. ß-brominated manganese porphyrins showed a lower GEN degradation (~ 25%) than the non-brominated ones (~ 35%), probably due to their steric hindrance. In any case, complete mineralization was achieved neither for NOR nor for GEN, and the assignment of the generated products, complemented by the study of their toxicity, was an important step performed. From the obtained results, no correlation was found between the number of identified products and the reported toxicity value (rSpearman,NOR = 0.006; p value = 0.986 and rSpearman,GEN = - 0,198; p value = 0.583), which reinforces the idea of synergism and antagonistic phenomena. The higher degradation degree could have led to products of lower steric hindrance and easier penetration into the A. fischeri cells, which subsequently led to an increase in toxicity for these experiments. In most cases, the products presented higher toxicity than the original compound, which raises a concern about their occurrence in environmental matrices.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Porfirinas / Manganeso Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Porfirinas / Manganeso Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Alemania