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Pressurized Extraction as an Opportunity to Recover Antioxidants from Orange Peels: Heat treatment and Nanoemulsion Design for Modulating Oxidative Stress.
Castro-Vázquez, Lucía; Lozano, María Victoria; Rodríguez-Robledo, Virginia; González-Fuentes, Joaquín; Marcos, Pilar; Villaseca, Noemí; Arroyo-Jiménez, Maria Mar; Santander-Ortega, Manuel J.
Afiliación
  • Castro-Vázquez L; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Lozano MV; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Rodríguez-Robledo V; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • González-Fuentes J; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Marcos P; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Villaseca N; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Arroyo-Jiménez MM; Analytical Chemistry and Food Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
  • Santander-Ortega MJ; Pharmaceutical Technology Area, Faculty of Pharmacy, University of Castilla-La Mancha (UCLM), Avda. Doctor Jose María Sanchez Ibañez. S/N c.p., 02008 Albacete, Spain.
Molecules ; 26(19)2021 Sep 30.
Article en En | MEDLINE | ID: mdl-34641471
Orange peel by-products generated in the food industry are an important source of value-added compounds that can be potentially reused. In the current research, the effect of oven-drying (50-70 °C) and freeze-drying on the bioactive compounds and antioxidant potential from Navelina, Salustriana, and Sanguina peel waste was investigated using pressurized extraction (ASE). Sixty volatile components were identified by ASE-GC-MS. The levels of terpene derivatives (sesquitenenes, alcohols, aldehydes, hydrocarbons, and esters) remained practically unaffected among fresh and freeze-dried orange peels, whereas drying at 70 °C caused significative decreases in Navelina, Salustriana, and Sanguina peels. Hesperidin and narirutin were the main flavonoids quantified by HPLC-MS. Freeze-dried Sanguina peels showed the highest levels of total-polyphenols (113.3 mg GAE·g-1), total flavonoids (39.0 mg QE·g-1), outstanding values of hesperedin (187.6 µg·g-1), phenol acids (16.54 mg·g-1 DW), and the greatest antioxidant values (DPPH•, FRAP, and ABTS•+ assays) in comparison with oven-dried samples and the other varieties. Nanotechnology approaches allowed the formulation of antioxidant-loaded nanoemulsions, stabilized with lecithin, starting from orange peel extracts. Those provided 70-80% of protection against oxidative UV-radiation, also decreasing the ROS levels into the Caco-2 cells. Overall, pressurized extracts from freeze-drying orange peel can be considered a good source of natural antioxidants that could be exploited in food applications for the development of new products of commercial interest.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Extractos Vegetales / Estrés Oxidativo / Citrus sinensis / Polifenoles / Antioxidantes Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Extractos Vegetales / Estrés Oxidativo / Citrus sinensis / Polifenoles / Antioxidantes Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza