Long noncoding RNA Gas5 induces cell apoptosis and inhibits tumor growth via activating the CHOP-dependent endoplasmic reticulum stress pathway in human hepatoblastoma HepG2 cells.

Zhang, Wei-Yi; Zhan, Hao-Lian; Li, Ming-Kai; Wu, Guan-Di; Liu, Zhe; Wu, Ling-Fei

Zhang, Wei-Yi; Zhan, Hao-Lian; Li, Ming-Kai; Wu, Guan-Di; Liu, Zhe; Wu, Ling-Fei.

Afiliación

Zhang WY; Department of Gastroenterology, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China.
Zhan HL; Department of Gastroenterology, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China.
Li MK; Department of Gastroenterology, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China.
Wu GD; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province, China.
Liu Z; Department of Gastroenterology, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China.
Wu LF; Department of Gastroenterology, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China.

J Cell Biochem ; 123(2): 231-247, 2022 02.

Article en En | MEDLINE | ID: mdl-34636091

Asunto(s)

Apoptosis; Estrés del Retículo Endoplásmico; Proteínas de Neoplasias/metabolismo; ARN Largo no Codificante/metabolismo; ARN Neoplásico/metabolismo; Transducción de Señal; Factor de Transcripción CHOP/metabolismo; Adulto; Anciano; Femenino; Células Hep G2; Humanos; Masculino; Persona de Mediana Edad; Proteínas de Neoplasias/genética; ARN Largo no Codificante/genética; ARN Neoplásico/genética; Factor de Transcripción CHOP/genética

Palabras clave

CHOP; GRP78; HepG2; endoplasmic reticulum stress; hepatocellular carcinoma; lncRNA Gas5

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Neoplásico / Transducción de Señal / Apoptosis / Factor de Transcripción CHOP / Estrés del Retículo Endoplásmico / ARN Largo no Codificante / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cell Biochem Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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