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Primary cutaneous lymphomas in children: A prospective study from the Spanish Academy of Dermatology and Venereology (AEDV) Primary Cutaneous Lymphoma Registry.
Torre-Castro, Juan; Estrach, Teresa; Peñate, Yeray; Acebo, Elvira; Fernández de Misa, Ricardo; Blanes, Mar; Suh-Oh, Hae Jin; Botella-Estrada, Rafael; Torrelo, Antonio; García-Doval, Ignacio; Machan, Salma.
Afiliación
  • Torre-Castro J; Department of Dermatology, Hospital Fundación Jiménez Díaz, Madrid, Spain.
  • Estrach T; Department of Dermatology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain.
  • Peñate Y; Department of Dermatology, Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas, Spain.
  • Acebo E; Department of Dermatology, Hospital Universitario de Cruces, Bizkaia, Spain.
  • Fernández de Misa R; Department of Dermatology, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.
  • Blanes M; Department of Dermatology, Hospital General Universitario de Alicante, Alicante, Spain.
  • Suh-Oh HJ; DIPO Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Pontevedra, Spain.
  • Botella-Estrada R; Department of Dermatology, Hospital Universitario la Fé, Valencia, Spain.
  • Torrelo A; Facultad de Medicina, Universidad de Valencia, Valencia, Spain.
  • García-Doval I; Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
  • Machan S; Fundación Piel Sana AEDV, Unidad de Investigación, Madrid, Spain.
Pediatr Dermatol ; 38(6): 1506-1509, 2021 Nov.
Article en En | MEDLINE | ID: mdl-34632613
BACKGROUND/OBJECTIVES: Primary cutaneous lymphomas are rare in pediatric patients. The clinical and histopathological manifestations may differ from those in adults. Due to their low frequency and the insidious clinical picture, the diagnosis is usually delayed. The Spanish Primary Cutaneous Lymphoma Registry was initiated in 2016 as a multicenter registry that would allow better insight into the epidemiological, clinical, histopathological, and treatment response characteristics of patients with primary cutaneous lymphomas. METHODS: We conducted a prospective observational cohort study of primary cutaneous lymphomas in pediatric patients participating in the Spanish Academy of Dermatology and Venereology (AEDV) Primary Cutaneous Lymphoma Registry. RESULTS: At the time of the analysis, 10 patients under 18 years of age out of 799 all-age cases (1.25%) had been included in the registry (7 males, 3 females). The mean age at diagnosis was 9.7 years (SD: 4.8). Seven (70%) had mycosis fungoides, 2 of them had the folliculotropic variant; and 3 (30%) had primary cutaneous marginal zone B-cell lymphoma. CONCLUSIONS: Primary cutaneous lymphomas are extremely rare in pediatric patients and usually have a good prognosis. Therefore, a high level of suspicion is necessary for the diagnosis. We suggest management by experienced physicians and follow-up into adulthood.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Venereología / Micosis Fungoide / Dermatología Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Humans Idioma: En Revista: Pediatr Dermatol Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Venereología / Micosis Fungoide / Dermatología Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Humans Idioma: En Revista: Pediatr Dermatol Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos