Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis.

Huang, Hei-Jen; Chen, Jie-Ling; Liao, Jian-Fu; Chen, Yu-Hsin; Chieu, Min-Wei; Ke, Ya-Yun; Hsu, Chih-Chieh; Tsai, Ying-Chieh; Hsieh-Li, Hsiu Mei

Huang, Hei-Jen; Chen, Jie-Ling; Liao, Jian-Fu; Chen, Yu-Hsin; Chieu, Min-Wei; Ke, Ya-Yun; Hsu, Chih-Chieh; Tsai, Ying-Chieh; Hsieh-Li, Hsiu Mei.

Afiliación

Huang HJ; Department of Nursing, MacKay Junior College of Medicine, Nursing and Management, Taipei, 11260, Taiwan.
Chen JL; Department of Life Science, National Taiwan Normal University, Taipei, 11677, Taiwan.
Liao JF; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.
Chen YH; Department of Nursing, MacKay Junior College of Medicine, Nursing and Management, Taipei, 11260, Taiwan.
Chieu MW; Department of Nursing, MacKay Junior College of Medicine, Nursing and Management, Taipei, 11260, Taiwan.
Ke YY; Department of Life Science, National Taiwan Normal University, Taipei, 11677, Taiwan.
Hsu CC; Bened Biomedical Co., Ltd., Taipei, 10448, Taiwan.
Tsai YC; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan. tsaiyc@ym.edu.tw.
Hsieh-Li HM; Department of Life Science, National Taiwan Normal University, Taipei, 11677, Taiwan. hmhsieh@ntnu.edu.tw.

BMC Complement Med Ther ; 21(1): 259, 2021 Oct 09.

Article en En | MEDLINE | ID: mdl-34627204

Asunto(s)

Disfunción Cognitiva/prevención & control; Lactobacillus plantarum/metabolismo; Fármacos Neuroprotectores/farmacología; Enfermedad de Alzheimer; Animales; Modelos Animales de Enfermedad; Gliosis/metabolismo; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Propionatos/metabolismo; Estreptozocina/administración & dosificación

Palabras clave

Cognition; Gliosis; Glycogen synthase kinase 3 beta; PS128 psychobiotic; Propionic acid; Streptozotocin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos Neuroprotectores / Lactobacillus plantarum / Disfunción Cognitiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: BMC Complement Med Ther Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Reino Unido

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