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The Effect of Resveratrol on the Cardiovascular System from Molecular Mechanisms to Clinical Results.
Gal, Roland; Deres, Laszlo; Toth, Kalman; Halmosi, Robert; Habon, Tamas.
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  • Gal R; Division of Cardiology, 1st Department of Medicine, Medical School, University of Pecs, 7624 Pecs, Hungary.
  • Deres L; Szentágothai Research Centre, University of Pecs, 7624 Pecs, Hungary.
  • Toth K; Division of Cardiology, 1st Department of Medicine, Medical School, University of Pecs, 7624 Pecs, Hungary.
  • Halmosi R; Szentágothai Research Centre, University of Pecs, 7624 Pecs, Hungary.
  • Habon T; Division of Cardiology, 1st Department of Medicine, Medical School, University of Pecs, 7624 Pecs, Hungary.
Int J Mol Sci ; 22(18)2021 Sep 21.
Article en En | MEDLINE | ID: mdl-34576315
Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective effects of natural polyphenols such as resveratrol (3,5,4-trihydroxystilbene) have been extensively investigated throughout recent decades. Many studies of RES have focused on its favorable effects on pathological conditions related to cardiovascular diseases and their risk factors. The aim of this review was to summarize the wide beneficial effects of resveratrol on the cardiovascular system, including signal transduction pathways of cell longevity, energy metabolism of cardiomyocytes or cardiac remodeling, and its anti-inflammatory and antioxidant properties. In addition, this paper discusses the significant preclinical and human clinical trials of recent years with resveratrol on cardiovascular system. Finally, we present a short overview of antiviral and anti-inflammatory properties and possible future perspectives on RES against COVID-19 in cardiovascular diseases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Sistema Cardiovascular / Resveratrol / Tratamiento Farmacológico de COVID-19 / Antiinflamatorios / Antioxidantes Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Sistema Cardiovascular / Resveratrol / Tratamiento Farmacológico de COVID-19 / Antiinflamatorios / Antioxidantes Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Suiza