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Experimental use of prostaglandin E2 (Dinoprost) in the treatment of duodenal ulcer in humans.
Prostaglandins Leukot Med ; 21(1): 97-105, 1986 Jan.
Article en En | MEDLINE | ID: mdl-3456621
Oral administration of 20 mg PGE2/day/patient (5 mg every 4 hours, 4 times a day) promptly relieved pain in 10 patients suffering from duodenal ulcer. After 3 days of treatment, the ulceration--observed by radiologic and gastrofibroscopic means--diminished by 30% in dimensions, and after 10 days, it almost disappeared. The results were compared with those observed in a placebo-group, who received 20 mg lactose/day/patient and with those in another group treated by sodium bicarbonate.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prostaglandinas E / Úlcera Duodenal Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Prostaglandins Leukot Med Año: 1986 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prostaglandinas E / Úlcera Duodenal Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Prostaglandins Leukot Med Año: 1986 Tipo del documento: Article Pais de publicación: Reino Unido