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BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Bittner, Zsófia Agnes; Liu, Xiao; Mateo Tortola, Maria; Tapia-Abellán, Ana; Shankar, Sangeetha; Andreeva, Liudmila; Mangan, Matthew; Spalinger, Marianne; Kalbacher, Hubert; Düwell, Peter; Lovotti, Marta; Bosch, Karlotta; Dickhöfer, Sabine; Marcu, Ana; Stevanovic, Stefan; Herster, Franziska; Cardona Gloria, Yamel; Chang, Tzu-Hsuan; Bork, Francesca; Greve, Carsten L; Löffler, Markus W; Wolz, Olaf-Oliver; Schilling, Nadine A; Kümmerle-Deschner, Jasmin B; Wagner, Samuel; Delor, Anita; Grimbacher, Bodo; Hantschel, Oliver; Scharl, Michael; Wu, Hao; Latz, Eicke; Weber, Alexander N R.
Afiliación
  • Bittner ZA; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Liu X; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Mateo Tortola M; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Tapia-Abellán A; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Shankar S; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Andreeva L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Mangan M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.
  • Spalinger M; Institute of Innate Immunity, University Hospital Bonn, Bonn, Germany.
  • Kalbacher H; German Center for Neurodegenerative Diseases, Bonn, Germany.
  • Düwell P; Department for Gastroenterology and Hepatology, University Hospital Zürich and University of Zürich, Zürich, Switzerland.
  • Lovotti M; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
  • Bosch K; Institute of Innate Immunity, University Hospital Bonn, Bonn, Germany.
  • Dickhöfer S; Institute of Innate Immunity, University Hospital Bonn, Bonn, Germany.
  • Marcu A; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Stevanovic S; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Herster F; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Cardona Gloria Y; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Chang TH; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Bork F; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Greve CL; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Löffler MW; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Wolz OO; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Schilling NA; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Kümmerle-Deschner JB; Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Tübingen, Germany.
  • Wagner S; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany.
  • Delor A; Cluster of Excellence 2180, Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany.
  • Grimbacher B; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Hantschel O; Institute of Organic Chemistry, University of Tübingen, Tübingen, Germany.
  • Scharl M; Division of Pediatric Rheumatology and Autoinflammation Reference Center Tübingen, Department of Pediatrics, University Hospital Tübingen, Tübingen, Germany.
  • Wu H; Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
  • Latz E; Cluster of Excellence 2124, Controlling Microbes to Fight Infection, University of Tübingen, Tübingen, Germany.
  • Weber ANR; Centre of Chronic Immunodeficiency, University Hospital Freiburg, Freiburg, Germany.
J Exp Med ; 218(11)2021 11 01.
Article en En | MEDLINE | ID: mdl-34554188
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tirosina / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Agammaglobulinemia Tirosina Quinasa Límite: Animals Idioma: En Revista: J Exp Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tirosina / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Agammaglobulinemia Tirosina Quinasa Límite: Animals Idioma: En Revista: J Exp Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos