Estradiol and progesterone binding in uterine leiomyomata and pregnant myometrium.
Clin Exp Obstet Gynecol
; 14(3-4): 155-60, 1987.
Article
en En
| MEDLINE
| ID: mdl-3454723
In order to verify the endogenous steroid influences on the myometrium, we compared the receptor status in 18 specimens of uterine leiomyomata and 31 specimens of pregnant myometrium. 17-beta-Estradiol and Progesterone receptors were assayed in the cytosol and nuclear extracts. In the uterine leiomyomata we observed the following mean values: PgR/c 279 fmol/mg, PgR/n 89 fmol/mg, ER/c 52.5 fmol/mg, ER/n 12.3 fmol/mg. In the pregnant myometrium we observed the following mean values: PgR/c 5.86 fmol/mg, PgR/n 166 fmol/mg, ER/c 0.76 fmol/mg, ER/n 1.65. It was concluded that direct correlation between estrogen power and progesterone receptor replenishment in the nucleus exists.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Progesterona
/
Neoplasias Uterinas
/
Receptores de Estradiol
/
Receptores de Progesterona
/
Receptores de Estrógenos
/
Estradiol
/
Leiomioma
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Clin Exp Obstet Gynecol
Año:
1987
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Singapur