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Identification of a PCSK9-LDLR disruptor peptide with in vivo function.
Brousseau, Margaret E; Clairmont, Kevin B; Spraggon, Glen; Flyer, Alec N; Golosov, Andrei A; Grosche, Philipp; Amin, Jakal; Andre, Jerome; Burdick, Debra; Caplan, Shari; Chen, Guanjing; Chopra, Raj; Ames, Lisa; Dubiel, Diana; Fan, Li; Gattlen, Raphael; Kelly-Sullivan, Dawn; Koch, Alexander W; Lewis, Ian; Li, Jingzhou; Liu, Eugene; Lubicka, Danuta; Marzinzik, Andreas; Nakajima, Katsumasa; Nettleton, David; Ottl, Johannes; Pan, Meihui; Patel, Tajesh; Perry, Lauren; Pickett, Stephanie; Poirier, Jennifer; Reid, Patrick C; Pelle, Xavier; Seepersaud, Mohindra; Subramanian, Vanitha; Vera, Victoria; Xu, Mei; Yang, Lihua; Yang, Qing; Yu, Jinghua; Zhu, Guoming; Monovich, Lauren G.
Afiliación
  • Brousseau ME; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: margaret.brousseau@novartis.com.
  • Clairmont KB; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Spraggon G; Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.
  • Flyer AN; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Golosov AA; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Grosche P; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Amin J; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Andre J; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Burdick D; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Caplan S; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Chen G; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Chopra R; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Ames L; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Dubiel D; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Fan L; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Gattlen R; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Kelly-Sullivan D; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Koch AW; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Lewis I; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Li J; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Liu E; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Lubicka D; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Marzinzik A; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Nakajima K; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Nettleton D; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Ottl J; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Pan M; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Patel T; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Perry L; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Pickett S; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Poirier J; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Reid PC; PeptiDream, Inc., KOL Building, Room 405, 4-6-1 Komaba, Meguro-Ku, Tokyo 153-8904, Japan.
  • Pelle X; Novartis Institutes for BioMedical Research, Fabrikstrasse 2, Novartis Campus, 4056 Basel, Switzerland.
  • Seepersaud M; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Subramanian V; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Vera V; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Xu M; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Yang L; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Yang Q; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Yu J; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Zhu G; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Monovich LG; Novartis Institutes for BioMedical Research, 22 Windsor Street and 181 Massachusetts Avenue, Cambridge, MA 02139, USA.
Cell Chem Biol ; 29(2): 249-258.e5, 2022 02 17.
Article en En | MEDLINE | ID: mdl-34547225
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Receptores de LDL / Proproteína Convertasa 9 Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Receptores de LDL / Proproteína Convertasa 9 Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos