Embryonic Ectoderm Development (EED) as a Novel Target for Cancer Treatment.

Cook, Nicholas; Chen, Jianping; Zhou, Jia; Wu, Daqing

Cook, Nicholas; Chen, Jianping; Zhou, Jia; Wu, Daqing.

Afiliación

Cook N; Department of Biological Sciences, Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314,United States.
Chen J; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555,United States.
Zhou J; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555,United States.
Wu D; Department of Biological Sciences, Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314,United States.

Curr Top Med Chem ; 21(31): 2771-2777, 2021.

Article en En | MEDLINE | ID: mdl-34544341

Asunto(s)

Terapia Molecular Dirigida; Neoplasias/tratamiento farmacológico; Neoplasias/metabolismo; Complejo Represivo Polycomb 2/antagonistas & inhibidores; Sitio Alostérico; Animales; Histonas/química; Histonas/metabolismo; Humanos; Metilación; Complejo Represivo Polycomb 2/química; Complejo Represivo Polycomb 2/metabolismo

Palabras clave

Cancer; Degrader.; EED; EZH2; Inhibitor; PRC2

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Molecular Dirigida / Complejo Represivo Polycomb 2 / Neoplasias Límite: Animals / Humans Idioma: En Revista: Curr Top Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Emiratos Árabes Unidos

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