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A retrospective, observational study on medication for opioid use disorder during pregnancy and risk for neonatal abstinence syndrome.
Sujan, Ayesha; Cleary, Emma; Douglas, Edie; Aujla, Rubin; Boyars, Lisa; Smith, Claire; Guille, Constance.
Afiliación
  • Sujan A; Division of Research, Kaiser Permanente Northern California, Oakland, CA, United States.
  • Cleary E; Department of Psychological and Brain Sciences, Indiana University-Bloomington, Bloomington, IN, United States.
  • Douglas E; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States.
  • Aujla R; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States.
  • Boyars L; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States.
  • Smith C; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States.
  • Guille C; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States.
Fam Pract ; 39(2): 311-315, 2022 03 24.
Article en En | MEDLINE | ID: mdl-34537839
Medications for opioid use disorder (MOUD), such as buprenorphine and methadone, are effective in reducing the significant harms associated with untreated opioid use disorder (OUD) in nonpregnant and pregnant adults. While previous research clearly documents that the risks of MOUD in pregnancy are less than the risks of untreated OUD in pregnancy, researchers have called for additional studies evaluating the safety of MOUD during pregnancy, particularly the relative safety of methadone and buprenorphine. In a clinical sample of infants born to women with OUD, we showed that buprenorphine-exposed infants were at significantly reduced risk for neonatal abstinence syndrome compared with methadone-exposed infants. Our study adds to the growing body of evidence supporting the use of buprenorphine over methadone for the treatment of OUD among pregnant women.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Buprenorfina / Síndrome de Abstinencia Neonatal / Trastornos Relacionados con Opioides Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Infant / Newborn / Pregnancy Idioma: En Revista: Fam Pract Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Buprenorfina / Síndrome de Abstinencia Neonatal / Trastornos Relacionados con Opioides Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Infant / Newborn / Pregnancy Idioma: En Revista: Fam Pract Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido