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The modulatory role of prime identified compounds in Geophila repens in mitigating scopolamine-induced neurotoxicity in experimental rats of Alzheimer's disease via attenuation of cholinesterase, ß-secretase, MAPt levels and inhibition of oxidative stress imparts inflammation.
Dash, Umesh Chandra; Swain, Sandeep Kumar; Kanhar, Satish; Banjare, Purusottam; Roy, Partha Pratim; Dandapat, Jagneshwar; Sahoo, Atish Kumar.
Afiliación
  • Dash UC; Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest & Environment Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India.
  • Swain SK; Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest & Environment Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India.
  • Kanhar S; Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest & Environment Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India.
  • Banjare P; Division of Pharmaceutical & Medicinal Chemistry, Institute of Pharmacy, Guru Ghasidas University, Bilaspur, 495009, Chhattisgarh, India.
  • Roy PP; Division of Pharmaceutical & Medicinal Chemistry, Institute of Pharmacy, Guru Ghasidas University, Bilaspur, 495009, Chhattisgarh, India.
  • Dandapat J; Department of Biotechnology, Utkal University, Vani Vihar, Bhubaneswar, 751004, India.
  • Sahoo AK; Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest & Environment Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India. Electronic address: atish_kumar1976@yahoo.co.in.
J Ethnopharmacol ; 282: 114637, 2022 Jan 10.
Article en En | MEDLINE | ID: mdl-34534598
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Proteínas tau / Agaricales / Secretasas de la Proteína Precursora del Amiloide / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Proteínas tau / Agaricales / Secretasas de la Proteína Precursora del Amiloide / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Irlanda