IgG4-Related Disease With Renal and Pulmonary Involvement.

Osuorji, Chinenye; Master, Kiron; Osuorji, Ikenna

Osuorji, Chinenye; Master, Kiron; Osuorji, Ikenna.

Afiliación

Osuorji C; Internal Medicine, Burrell College of Osteopathic Medicine, Las Cruces, USA.
Master K; Radiology, Hospitals of Providence Sierra Campus, El Paso, USA.
Osuorji I; Hematology and Oncology, Burrell College of Osteopathic Medicine, Las Cruces, USA.

Cureus ; 13(8): e17071, 2021 Aug.

Article en En | MEDLINE | ID: mdl-34522549

RESUMEN

Immunoglobulin G4-related disease (IgG4-RD) is a rare immune-mediated disease affecting multiple organs and tissues. There is often the presence of elevated serum Ig4 subtype with histological evidence of lymphoplasmacytic infiltration, fibrosis, and phlebitis. The mainstay of treatment is steroids therapy. We report the case of a 66-year-old man presenting with acute on chronic renal failure and pulmonary nodules seen on PET-CT scan. He also had elevated serum IgG4 subclass and histological features in keeping with IgG4-RD. He failed steroid therapy but responded subsequently to rituximab with complete resolution of his symptoms.

Palabras clave

igg4 -related disease; lung nodules; plasma cells; storiform fibrosis; tubulointerstitial fibrosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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