Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability.

Khatri, Bhavesh; Raghunathan, Shampa; Chakraborti, Sohini; Rahisuddin, R; Kumaran, S; Tadala, Raghu; Wagh, Padmakar; Priyakumar, U Deva; Chatterjee, Jayanta

Khatri, Bhavesh; Raghunathan, Shampa; Chakraborti, Sohini; Rahisuddin, R; Kumaran, S; Tadala, Raghu; Wagh, Padmakar; Priyakumar, U Deva; Chatterjee, Jayanta.

Afiliación

Khatri B; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, 560012, India.
Raghunathan S; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.
Chakraborti S; Present Address: École Centrale School of Engineering, Mahindra University, Hyderabad, 500043, India.
Rahisuddin R; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, 560012, India.
Kumaran S; CSIR- Institute of Microbial Technology, Chandigarh 1, 60036, India.
Tadala R; CSIR- Institute of Microbial Technology, Chandigarh 1, 60036, India.
Wagh P; Waters Corporation, Bangalore, 560058, India.
Priyakumar UD; Waters Corporation, Bangalore, 560058, India.
Chatterjee J; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.

Angew Chem Int Ed Engl ; 60(47): 24870-24874, 2021 11 15.

Article en En | MEDLINE | ID: mdl-34519402

Asunto(s)

Oxígeno/química; Péptidos/química; Proteínas/química; Azufre/química; Estabilidad Proteica

Palabras clave

isostere; proteomimetics; solvation; thermostability; thioamide

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxígeno / Péptidos / Azufre / Proteínas Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania

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